I had my first infusion End of March and second 1st week in April. There has been no improvement and I saw my consultant this morning and he is of the opinion it isn't going to work. Has anyone been on this drug and how did you get on with it? I have had X-ray's this morning and Blood Tests and it has been decided to wait for the results before deciding the next step. It is all rather complicated due to my having Multiple Sclerosis as well and most drugs make the MS worse.