Latest on CAR T-cell therapy

[Shar0n]

"Work has already begun on trials to evaluate CAR T-cell therapy in earlier stages of disease and in other types of hematologic malignancies, especially other forms of NHL, which collectively has 72,000 new diagnoses each year"

medpagetoday.com/hematology...

[wmay13241]

In November 2011, at the age of 64, my wife was diagnosed with follicular lymphoma Stage 4, Grade 3A. She had 50% bone marrow involvement. She is one of the 20% of follicular lymphoma patients who progress rapidly after treatments. In 3 years she progressed after R-CHOP (6 cycles), bendamustine/rituximab (6 cycles), and Ibrutinib (12 months). Then she took Idelalisib/rituximab as her fourth treatment. It worked great for 14 months then a PET scan showed she progressed again. She is now in an NIH CAR-T trial NCT02659943 was infused on March 2, 2016. As of January 3, 2018 she has been in complete remission for 22 months. Clinical trial studies show that CAR-T cells may result in long-lasting remissions for some people who have follicular lymphoma. There is more information on CAR-T for fNHL patients and people considering CAR-T at fnhlben.wordpress.com/

Other non-Hodgkin lymphoma sites I visit often are:

lymphobob.blogspot.com/

lymphomation.org/#what-is-new

lymphoma.org/ (look for free "Ask the Doctor" meetings near where you live)

lls.org/