Vitamin

[gpr52]

Is anyone taking a vitamin (Niacinamide) to reduce the cause of skin cancers?

My new dermatologist has asked me to take the vitamin and I am reluctant to add a medication/vitamin to my immunosuppression medications for fear of a rejection.

[Denise-80]

Not me, but following this post.

[LauraW4Jc]

My dermatologist recommended I take niacinamide after a number of skin cancers. I have been taking it for about a year with no negative side effects at all but I have had a reduction in the number of skin cancers.

[gpr52 in reply to LauraW4Jc]

Laura,Thank you. My immunosuppressive meds are Prograf and prednisone. I’m concerned different meds may react differently. May I ask if you take these meds?

[LauraW4Jc in reply to gpr52]

I take Prograf, Zortress and just went off Prednisone

[KathleenMA]

I haven’t heard of this med so googled and found this article ncbi.nlm.nih.gov/pmc/articl.... Interesting but I’m leery of taking any supplements too. I would ask your dermatologist to clear with your transplant team or nephrologist. My derm does this all the time for even topical treatments.

[LisaSnow]

Niacinamide 500mg twice a day has shown to decrease new skin cancer significantly. I take it so does my husband who has a family history of skin cancer. No side effects and it is really just like a multi vitamin. Benefits significantly outweigh any (non observable) risk.

[PostivelyJo in reply to LisaSnow]

I just had a biopsy done last week although they think it’s nothing it was good to get checked out. First time since transplant almost 3 years ago . Definitely going to get Niacinimide .will dble check with team first .

Thanks Lisa . Brilliant advice as always !

[LisaSnow]

Please read this New England Journal of Medicine report nejm.org/doi/full/10.1056/n...

[Transplant2018]

I also take it based on recommendation from my dermatologist and after discussion with my nephrologist.

[gpr52 in reply to Transplant2018]

Thank you for your reply. So very grateful.

[LisaSnow]

Skin cancers made up for almost 40% of malignancies in transplant recipients, and they develop in more than 50% of White transplant recipients. The fact that it happens so frequently makes it a serious health problem in transplant population and is one of the reasons why clinical trials were conducted for this supplement. Prevention is everything when it comes to skin cancer. I hope you would consider taking it as advised!

For the worries about bad interactions with other medications, your transplant team would know answers better than us. With the ones you shared already there are no concerns, but you may be on others so it is best to verify with your team.

[gpr52 in reply to LisaSnow]

Lisa,Thank you so much for your reply.

Your information is encouraging. I hope to speak to the transplant department next week just for reassurance.

I appreciate you being so kind.

Stay healthy.

[donnabethme]

Some immunosupressing meds have cancer m, especially skin cancer as a side effect. You should consult with your nephrologist but I have never heard of a “ vitamin” causing rejection. But it might not prevent cancer either.

[gpr52 in reply to donnabethme]

Thank you for your input. I appreciate all the comments on my question. All of you have been so helpful. Stay healthy.

[Tran50years]

Niacinamide dropped my skin cancer incidence in half. I take 500 mg twice a day. There have been clinical trials showing positive effect.