Anyone here on glyxambi?? I have been, am. But drugs.com says that ckd patients with stage 3 or lower should not be on glyxambi??? So I am dc'ing it effective immediately. Will be a month before I see my pcp who prescribed it many months ago. egfr has dropped from 60 in February to 49 now in October and creatinine now up to 1.4. Either I am the dumbest patient that exists or my pcp has overlooked this. God knows what the right answer is. Blood sugar has never been better thanks to free style libre and bp also has never been better since losing 15 pounds. Still my egfr dropping. Have begged my nephrologist to actually see me after being his patient for 8 months so maybe he has thoughts on glyxambi. Anybody dealing with meds that might be killing you, would be glad to hear from you.
diving egfr: Anyone here on glyxambi?? I... - Kidney Disease
diving egfr
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Hi mickeyba1,
I'm not on that med but many meds will effect eGFR. My primary and Neph. switched around a couple of my meds and even the ones from the Neph. say they can effect the kidneys. It's often a matter of risk vs. benefit. Controlling your T2D with Glyxambi will ultimately help your CKD, but a different antihyperglycemic medication may work better for you. It is negligent that you can't see your Neph. for over 8 months. I'm going to be seeing mine every 3 months for the journey through my CKD. Can you call the Neph. and have the receptionist ask the question of him/her and get back to you? Or ask your primary to consult with the Neph. The two of them should be consulting on your treatment. My drs. write a note and send it electronically between them when either changes anything. I get an email copy of the note and all test results.
You are certainly not the dumbest patient, you are intelligent to be asking important questions that effect your health!!!! Please contact your PCP before discontinuing that drug so they can start you something else. You don't want to get your blood sugar out of whack along with your eGFR. Best of luck, I hope you find some med that works for you.
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Thanks so much Sophie. I intend to tell my pcp that meds should not be the first treatment choice. They have helped but at what cost. Have finally been given appt for neph next week.How willing he would be to suggest med changes, who knows. But for sure, diet changes have few to no side effects. All diabetic meds do and kidney stress is always one of them. So for now I am not taking my glyxambi, more concerned about preserving kidney life than lowering blood sugar. Last a1c was 6.3 God knows glyxambi producer does not say it will improve ones egfr.
It's great that you're looking for feedback. My hubby is a T2D who wound up on dialysis and recently received a transplant. Please be aware that it's your diabetes that created the damage - diabetes compromises and takes out the blood vessels in your kidneys, eyes, limbs, etc. So, the likely monster behind everything is the diabetes, not so much the diabetes meds. Unfortunately, it takes a couple of decades before one really becomes aware of diabetes' impact. You've done a wonderful thing in putting it in its place by losing the weight - you gave your body a huge gift right there. And you're wise in seeking out a "better" medication, if one is needed, for that condition.
In my hubby's case, he also lost a lot of weight by largely eliminating sugars and carbs in the effort to stave off dialysis. (Glucose is the abrasive that works against you.) While his numbers significantly improved for a time, they suddenly went in the wrong directions, seemingly overnight, placing him on dialysis. When we questioned the nephrologist, he simply stated that when kidneys have had enough, they can simply quit like that. My hubby was still on insulin at the time, but he managed to get off all diabetes meds shortly after being on dialysis. Throughout, our GP, with the blessing of our nephrologist, worked with his diet as the "renal dietician" didn't have the knowledge to work effectively with a diabetic diet and kidney diet - recommending sweet fruits, white bread, rice, etc. Sadly diabetes, while epidemic, tends to be ignored. Indeed, our dialysis center stated "almost all" there were diabetics.
The reason I'm bringing up our experience is so others can perhaps use it to stay ahead of everything - to look down the road with good clear vision. If we had played our cards right, dialysis could have been prevented either by diet earlier on or by skipping dialysis altogether, by getting on the transplant list sooner than later, etc. This said, I'd like to add that I think you're in position to be successful since you've already well on your way on that wellness journey! I would have loved seeing a creatinine level that you reported. Even with a transplant, my hubby's creatinine level is still higher than yours. I'm also impressed with your A1C level. And I wonder if your GFR number was simply an anomaly. I suspect you're well ahead of where my hubby was a few years ago. And I appreciate you being so proactive. Keep on keeping your eyes on the outcomes you want to see. I sense they may very well happen!
Thank you Darlenia. See my neph for first time in 8 months this coming week. Maintaining weight is a current problem, not allowed to have more carbs or protein. That only leaves fat so I have started pouring olive oil on my vegetables and a piece of bread and butter with every meal, hope I can reverse this weight loss. mickeyB