Which to choose?

[Cheerio_100]

Trying to get real world pros and cons of Tysabri vs Mavenclad. If bloodwork all comes back fine, I will have to decide on one of these. Currently on Aubagio but due to side effects, I am having to stop it. Thanks for any info you can give.

[BlanketTime1]

just wanted to wish you luck on your search.

[kdali]

MSAA has information about medications. Facebook has groups for people taking medications, and you can search there, just like you can here, for posts and comments. I've never taken Tysabri and have only been on Mavenclad a few months. I hear both are awesome choices!

[Kenu]

Don’t know about Mavenclad but was on Tysabri for seven years and did great 👍🏼 The only side effect was fatigue the next day. I had infusion done on Friday afternoon so I would be back to work on Monday. The only reason I stopped was throat cancer ♋️. Have been on seven different meds and Tysabri worked the best for me 👍🏼😉

[Frances_B]

They work differently and have different dosing schedules - Mavenclad (cladribine) is an induction therapy, while Tysabri (natalizumab) is a continuous therapy. It's probably worth your while doing some research into them and the way the work. Mavenclad is given in doses a year apart for two years, while Tysabri is an infusion monthly, or if on extended dosing schedule it can be six or eight weekly infusions. Some people on Tysabri complain about what is commonly called the "crap gap" - they feel pretty crappy in the week or few days immediately before their next infusion is due.

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If you test positive for the JC virus Tysabri probably won't be an option anyway.

[sashaming1]

Tysabri worked for me by stopping new MS lesions. It had a small risk of side effects but I chose to take it. I eventually tested positive after 10 years of monthly testing for the JC Virus so I stopped and took Lemtrada with no side effects. It is also working.

[JTZES]

As was just mentioned if your JVC positive Tysabri isn't a possibility but if your not it is the most effective DMT on the market. That's the direction I would go.

I would also explore Ocrevus or the latest approved Kasemta. Sorry for the spelling mistakes.

[Jesmcd2 CommunityAmbassador]

Hi Cheerio_100 MSAA just released the Ultimate Treatment Guide! Hopefully it will help you out! mymsaa.org/ms-information/t...

Good Luck 🤗💕🌠

[KipAngCan]

I am JVC positive and took Ocerevus for 2 years but I experienced the “crap gap” very much. My neuro sent me to a colleague with more MS experience and he switched me to Mavenclad. I’m in between yearly doses right now and have had no noticeable side effects. So far it appears to be working and has been a good experience. Good luck with whichever treatment you choose.