My doctor and I finally came to the conclusion that Ocrevus and Levothyroxine do not get along very well in my body. I had been taking Armor thyroid meds for years up until a year and a half ago when the drug became unavailable. I then had to change to levothyroxine. I had been on levothyroxine for about 6 months before my first Ocrevus infusion. Two weeks after my 1st full dose of Ocrevus I ended up in the hospital due to arrhythmia. That's when I found out that I had thyroid toxicity. My doctor was perplexed as to why all of a sudden I became toxic when my previous blood tests had come back ok. So we cut my medication dose in half. My hair started falling out more than usual but the arrhythmia had settled down. Three weeks after my 2nd full dose of Ocrevus my hair was falling out by the fist full and the arrhythmia had started in again. So the doctor had me cut my levothyroxine dose in half again. I did another blood test, again my levels were still in the normal range even after cutting my dosage.
I decided to check with my pharmacy to see if they can get Armor yet and YES it was available again. So my doctor changed my script to Armor. I am doing much better now, the arrhythmia has stopped and the hair loss has slowed down. The big test will be in October when I get my next Ocrevus infusion. I will know for sure if it was the levothyroxine or the Ocrevus causing the problems. I sure hope it was the levothyroxine cuz I really don't want to stop the Ocrevus since it is helping me so much.