Tecfidera Shows Promise as Replacement M... - My MSAA Community

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Tecfidera Shows Promise as Replacement MS Therapy for Tysabri, Study Shows

bxrmom profile image
7 Replies

I received an email about this today and thought others may be interested (created a shorter link): bit.ly/2wz0Jje

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bxrmom
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7 Replies
WAshingtongirl profile image
WAshingtongirl

Thanks, bxrmom . 💕

Juleigh21 profile image
Juleigh21

That was an interesting article. Thank you. I was on Tecfidera before Tysabri and had my worst relapse while using it. I'm doing very well on Tysabri and dread the day I can no longer use it😕. I'm following rituximab and ocrevus as alternatives if/when that dreadful day comes.

bxrmom profile image
bxrmom in reply toJuleigh21

Juleigh21 Sorry to hear you had such a bad relapse on the Tecfidera. Glad Tysabri is working well for you. Hopefully rituximab or ocrevus will be a good alternative when you can no longer use Tysabri.

Jessie

Sukie427 profile image
Sukie427

Hi and thanks for posting this. Tecfidera has much better odds for avoiding PML then does tysabri if you are jcv positive. I've been on tecfidera since it came on the market and other than a slight flushing every once in awhile I do very well on it and it seems to have kept lesions that day although my symptoms very in their progression. My doctor would never put me on by Sabri but he had no hesitation about the tecfidera. Interesting Lee, both drugs are made by Biogen.

bxrmom profile image
bxrmom

Sukie427 That is interesting that both drugs are made by Biogen but odds of PML are different but I suppose the ingredients are different.

Fancy1959 profile image
Fancy1959

Bxrmom, it's Fancy1959. The study was not the case for me. After being on Tysabri for about 9 months and having quite a bit of improvement on it I was switched to Tecfidera because of the risk I was facing being positive for the JC Virus. The first two years went very smoothly. Shortly after my 2 year anniversary I started to see an increase in the worsening of my symptoms. An MRI indicated I had had silent activity and my MS lesions had increased in both my brain and my spinal cord. I was then switched back to Tysabri but I never regained the functional use I had lost during my last silent attack. The post in the article and hopefully it helps many many people in chat room.

bxrmom profile image
bxrmom in reply toFancy1959

Fancy1959 I'm sorry that the Tecfidera made things go backwards for you. I had my 6 month blood work done yesterday and just received my blood work results from the hospital this morning and the numbers look good and have not changed too much so I'm happy about that. Test results are sent to 'mychart' for patients that go to any of the affiliate clinics of the hospital here so they can access results, refill rxs, etc. and I'm loving the new system they put in!!

Jessie

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