I have primary myelofibrosis (diagnosed March 2024) and am still learning what is and what isn’t associated with it. My resting heart rate is between 43-50 bpms. Blood pressure is fine (110/68 on average) and I am not an elite athlete.
Other than the low heart rate and cancer, pretty healthy 
Does anyone else have a low heart rate and if so, what have you been told by the medics. Mine don’t seem interested/concerned. It just seems odd that PMF and bradycardia happened at the same time.
I had the opposite issue, tachycardia, for which I had a catheter ablatio. Provide you are asymptomatic, you may be OK with the bradycardia; however, I would not assume so, particularly in the presence of a MPN. This is an issue that requires input from a cardiologist. Suggest you seek expert consultation on this issue.
best get it checked by a cardiologist, I havnt heard of it being MPN related, maybe also worth checking thyroid is not low, that can cause slower heart rate
Hello Scambria - I have been treated with propranolol in the past and also on another beta blocker. On both occasions my heart rate went down too low - actually to 45 - after only a short time on the drug.
The first time I was probably in my fifties and the second time in my seventies. I have been told not to take beta blockers again.
My resting heart rate is also very low, average of 45 this past year, at its lowest 43. It was low before my diagnosis but no idea if its been low all my life.Did have a heart issue last year when palpitations led me to referral to a cardiologist. After several tests an echo cardiogram gave me a diagnosis of pulmonary hypertension, however, the next echo cardiogram was normal and I was promptly discharged.
I have PV diagnosed November 2019, 2 years on hydro, then Ruxolitnib 20mg per day at the moment.
Was super healthy before diagnosis but now feel I'm falling apart, besides the heart scare, also had pressure issues in my eyes, and skin problems. Also experience the usual fatigue and shortness of breath, intermittent constipation, sometimes insomnia,and constantly burning legs.
However, I walk everyday and stay as active as I can, eat an anti inflammatory diet , and actually feel reasonably healthy compared to many of my peers. I am 73.
Sorry for the long post.
Slow HR, lowish BP, MPN..... SNAP .... I got all those plus a few others all probably unrelated (apart from the Pancreatic Insufficiency that has been linked to Coeliac disease).
We are all different and as we age our imperfections become more noticeable and noticed.
Try not to worry, keep active and relax!!!!!!!!!!
Hi, my heart rate is also low, similar to yours. I am on Rux which is known to damage the kidney. Nephrologist said that low blood pressure is good for the kidney. I have been on blood pressure medicine for years.
Hi Scambria. When you say resting, do you mean just sitting and resting or sleeping? My resting is usually 60-70bpm but sleeping rate can be in the 40s (according to my Apple Watch anyway)
I have bradycardia which was causing me to feel faint and so I visited my doctor . I then experienced tachycardia so the swing back and forth was deemed just throwing PVC’s. I visited my cardiologist and wore a halter monitor for 10 days. Since my episodes were less than 10% they just gave me a beta blocker. I took it and my heart rate went down to 38!
Went back to the cardiologist and he very clearly knows nothing about MPN’s.( I have ETJak2 with signs of developing PV. )
Going to MD Anderson in April and hope to gain some insight from my doctor there.
Does anyone else feel like this? 
Recently Diagnosed-ET-Does Fitness Suffer?
Does anyone else experience visual (ocular) migraines?
What does Anaemic mean ? 
