Absolute Eosinophil Count

[superburning628]

Hi I was wondering if any of you have a hi absolute Eosinophil Count in bloods and what it lead to as mine is always high Stuart

[hunter5582]

Eosinophils are leukocytes that are involved in allergies, fighting parasitic infections, and inflammatory response. They can be elevated in response to a number of conditions. Eosinophils can also be high as a result of a MPN.

You have a number of other conditions impacting you right now. It is plausible that the eosinophilia is the result of those conditions. Suggest that you consult with a MPN Specialist for the best explanation of the meaning of this finding.

it will help to have a basic understanding of what is shown on a CBC. Here is a good videa with a basic explanation of the CBC.

youtube.com/watch?v=Xj_yE1p...(Not working as expected?)

[superburning628 in reply to hunter5582]

Thanks for the information I will check it out

[JackEdwin in reply to hunter5582]

my husband has had high monocytes in addition to high eosinophils for several years. Also high PLT’s and finally dx’d with prefibrotic myelofibrosis by bone marrow biopsy. Are elevated monocytes also related to MPN’s? Thank you

[superburning628 in reply to JackEdwin]

Thankkyou

[hunter5582]

Yes. Monocytosis can be related to MPNs. The deregulation of the JAK-STAT pathway can cause elevation in other types of blood cells, not just platelets. Monocytosis can cause a number of MPN symptoms related to increased inflammation. Monocytes are an important part of immune response. Elevation can also occur due to infection.

A MPN Specialist can do the best job of providing a case specific explanation of the role of monocytosis in your husband's case. It is worth understanding how the factors that impact how our MPNs present and how to best intervene to improve symptoms.

Wishing you both all the best.

[superburning628 in reply to hunter5582]

Thankyou