Allele burden reduction!

[Lucylottie]

I have been on Pegasys for the two years since my diagnosis of PV at age 59, initially on a weekly dose of 45 mcg and for the last year on 67.5 a fortnight. My JAK2 allele burden was 34% at diagnosis but my 2 year test results have just come in a phone call from my very excited MPN specialist - my AB is now 2.1%!!!! I realise my PV journey could be a rollercoaster ride moving forward but I feel delighted with this news and will be keeping everything crossed that my allele burden remains this low and Pegasys remains available 🤞🏼I hope this result can offer some encouragement to others on this journey.

[dbus1417]

very cool. Hope it stays low! I think less than 1% is within detectability limits for the test 🤯

I’m curious how my ab is doing now 🫣

[ainslie]

congratulations, delighted to hear it’s going well for you

[Solyesh]

What great news! Yes let's hope they get the Pegasys supply sorted and quickly

[Spanelmad]

What a result!!

[hunter5582]

Great news. Glad to hear it. You may be one who reaches a molecular remission.

[kamiilos]

Well done Congratulations.

[Minify]

Was that a bone marrow or blood allele burden?

[Lucylottie in reply to Minify]

It was a blood test

[Franko21]

That’s such good news for you . I too hope Pegasys is sorted soon .

[ABPD]

Great news

[Lyndjs]

Brilliant, thank you for sharing 😊 so happy for you, gives us all hope xx

[lizzziep]

Good news!

[Looolooo]

Really great news! What all of us hope for.

[RedCardRob]

Great news after 2 years

[NickyRobinson]

Congratulations, it lovely to get great news, it’s always makes you feel a lot more positive when dealing with having an MPN ❤️

[Bluetop]

Good news to share! Hope it continues.

[Mishie14]

Congratulations! I am very happy for you and us MPNers who have another example of treatment that is working. Good job Lucylottie.

[Roxanne22]

Thanks Lucylottie. This is wonderful news and I am hoping that my trajectory is following a similar success story in year or two ahead. I started besremi this week, and have been delighted so far as no tangible side effects so far! And the first time no night sweats in years. Great start, however my main objective was to reduce AB which was around 77%. Fingers crossed and thank you for sharing your pos+ news! All the best.

[KLCTJC]

I needed this today! I did labs yesterday and will get results today. I always get so nervous and was looking for encouragement! This was it! I am so happy for you and thank you for this!