Hi everyone
I’ve had PV for 12 years or so and have been on Ruxolitinib for the past 7 years with great success. My platelets dropped to around 450 and my haematocrit has been stable, with no side effects. My general health and fatigue levels have improved markedly. However over the past 18 months my platelets have been increasing despite increases in my Ruxi dose from 20mg per day to 40mg per day. My platelets are now over 600. My other blood counts remain within range.
I don’t have any particular symptoms but I’m now worrying whether the benefits of Ruxi are diminishing, and wondered if there’s anyone out there who has had a similar experience? And what happens after I reach the notional maximum dose of 50mg per day?
Grateful for any thoughts. Thanks, Rob