This is a brief summary from October of 2023 of the promising progress being made in MPN treatment options. For anyone who has not seen it, it is worth watching.
Advances in Research | Emerging MPN Therapies on... - MPN Voice
Advances in Research | Emerging MPN Therapies on the Horizon
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Promising drugs on the horizon only can be good news!
Hunter this is amazing news. Thank you for sharing.
Thank you for sharing this good news Hunter! Hope one day we will cure MPN.
Thanks for sharing this, Hunter.
Thank you Hunter!
Exciting progress. One combo I didn't hear: IFN+Rux, this one is quite compelling. It's been shown despite apparent opposing effects, they are complementary. Rux may also soften some of IFN's harsher effects. (I can't try of course)
do you have more information on the combo of rux and interferon? I am on interferon and it is taking more than a year and a half to bring my platelets down and they are still a little high. I asked my oncologist about adding rux and he knew nothing about it so if I could get some information that would be great. Since I am feeling good on the interfere on, and was incredibly sick on hydroxy, I am reluctant to just stop the interferon.
Here is a post that discussed it in some detail. Note the red line in that plot is my addition, not part of the actual report.
healthunlocked.com/mpnvoice...
Here is another post from a member who has been actually using this combo:
healthunlocked.com/mpnvoice...
It's likely hard to get insurance coverage for this. What is your current PLT?
oops you asked my current platelets. They are in the 700s. When I was on hydroxy, I got them down down into the 500s and they stayed somewhat near there and then gradually went up. I did have a tooth infection for a while, so I was blaming it on the infection but my last bloods were about the same as the time before which was about 700. I get another draw in a week or two and will also retest my allele burden then. I am feeling very normal even though my platelet level is high, so I am reluctant to change medication. I am looking very interested in options that can be added to the interferon.
From my experience and a report discussed in a recent post, Rux may be less effective getting the lowest PLT values. At least it can take time. Mine seems to be leveling ~400 while on IFN and HU it was in mid 200's. But we all can have very different outcomes. The combo might be also effective here.
You were on a low IFN dose last year, is that still?
Thanks so much for sharing , Hunter! What a lovely optimistic post to start of 2024. Here's hoping for many meaningful advanced in treatment and hopefully cures very soon. Wishing you a healthy 2024 from NYC.
Many thanks and a fine new year to you!
Brilliant news - very positive and thanks for sharing.
Amazing! Thank you.
Thanks for sharing this Hunter. Very exciting possibilities if we can only keep going for another 5 years!
Plan to make it so to make it so. My Projected Age of Demise per the statistics is age 74, six years from now. To Bloody Hell with the PAD! I do not plan to die on a timer! There is no clock ticking away in my body. I am going to carry on with living a good life for as long as possible. With my current treatment plan, I plan to live well beyond the statistical projection. I plan for that time to be high quality time. However long it takes to reach my actual PAD, it is going to be a fun ride that is full of joy enjoyment and success. We should all plan to make it so.
Thank you so much for sharing! This is really interesting