I have been on Ruxolitinib for nearly 9 years now managing my primary myelofibrosis. I have been advised today that I now have a very high cholesterol level of 9.4. We went through my family history and diet but it seems that Rux seems to be the main contributory factor. The sheet does say this is a very common side effect of Rux ( raised blood cholesterol).. The strange thing is that my haematology team has never monitored this and it was discovered by my GP. Does anyone else on Ruxolitinib relate to this?
Ruxolitinib & raised cholesterol : I have been on... - MPN Voice
Ruxolitinib & raised cholesterol
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Hi. Yes, raised cholesterol appears to be a common side effect of Rux. It was one of the things raised by my haem (Guys Hospital) in a recent discussion about participating in a clinical trial where Rux is a possible drug option. I was told if my cholesterol started rising I’d be put on to statins.
Hi there! Yes - I am also struggling with raised chlorestorol due to run and I was offered statins by my GP. I refused them and I'm trying to control this with alterations to my diet. I'm going back to my GP at the end of November to have this checked again.
Hi there Cazbolac. Raised Cholesterol is a well-known side effect of Rux. I'm wondering if your doctor is an MPN specialist? Have you checked the list often provided on this thread? Statins ought to sort it out. High cholesterol isn't helpful for people with MPNs.
Best wishes
Agreed. A good GP is in valuable!
hi my chlorestoral is checked as part of normal blood tests quite frequently. I have only once had a fasting cholesterol test. I am on statins as I had a stroke. I’ve been on rux for 3 months. Chlorestoral has risen but is not dangerous- 4.