I am wondering if anyone else experienced this, I received my first Covid shot in April. Within the next 3 weeks I had my labs drawn for my monthly phlebotomy. Since 2016 my platelets have consistently been in the mid 700’s. After receiving the covid shot( that was the only difference in the norm) My platelets dropped to 311. I go back in for labs next week and Im curious to see if the platelets continue to drop or return to their normal 700’s
Has anyone else had this experience?
Hello. I have been diagnosed with ET (JAK2+) in January 2021. My platelets had been 590k. Had my first two doses of the Pfizer vaccine in April and June. In my semi-annual checkup (July 2021), my platelets were at 447k. I had the third dose in December of the same year. My platelets have been between 500k-560k ever since.
So yes, it happened to me but platelets do tend to fluctuate for various reasons. In my case, they seem positively connected to my stress levels and seasons (higher in winter, lower in summer) but I've found no scientific base for that either, purely my observations.
I do not take any medication other than aspirin for now.
That is quite a drop and almost scary but when it dropped it actually puts you back into normal levels unfortunately there was a story of a doctor in Florida who's platelets dropped so significantly he passed away in 2021 when the shots began so I would keep an eye on it I would say any shot vaccine or whatever that has the ability to change our platelets so drastically you might want to not keep doing that to yourself if you're a healthy person and antivirals are available to you. This is a pretty serious side effect and if you report it to fizer they will make a note of it but it won't really honestly go anywhere and your doctor will probably tell you it's no big deal because everyone wants you to keep getting more and more and more shots and they will deny that there are indeed side effects that go with it.
I’ve heard of it, best keep a close eye on it and prob discuss with Haem, as a joke it seems that the vaccines maybe better at lowering platelets than preventing Covid. Note I’m not anti vax but it’s a pity they weren’t better.
A sudden drop in PLT is a rare but known COVID vaccine adverse effect. Note that since you started off with thrombocytosis, your drop in PLT did not induce thrombocytopenia since your PLT were within normal limits.
"Estimates to date suggest that post–COVID vaccine ITP is rare (1 in 100,000 to 1 in 1,000,000) and may be related to vaccination or represent a coincidental event." hematology.org/covid-19/vac....
Mine temporarily dropped around 100 points. I am usually in the 800s.
Jakafi issues
Increase in platelets 
Covid Shot, benefit of side effects
Covid 
