Anyone been in both peg and Besremi? If so what side effects were common and what were different?
I have CALR Positive ET and was on weekly 45mcg peg for 4 years and it worked well. My usual side effects were some depression, increased upper abdominal pain, and mild flu like feeling for a day or two after injection. Toward the end I had developed a neuropathy that caused me to have weakness in my feet which still has no known cause after many neurological tests. Peg was initially suspected especially since my last dose caused extreme burning in my lower legs. So I stopped peg for a couple months then started on HU. The neuropathy (weakness main concern) has not improved while I’ve been on HU for past couple years and want to try Besremi to see if it works without the neuropathic pain.
Thanks for any replies.