Second malignancies side effects in hydroxyurea

[Paul1993et]

Hydrea is still considered by many practitioners as the first choice therapy for ET and PV:

Patients treated with HU had a significantly higher risk of developing all second malignancies..

onlinelibrary.wiley.com/doi...

And

pubmed.ncbi.nlm.nih.gov/247...

This again shows the great need for better treatment of MPN..

[hunter5582]

These findings have been known for some time now. It is all about risks and benefits with any med. Agree that it shows the need for better treatment options. I would add that it also reflects a need for providers to do a better job with fully informed consent when recommending HU or any other medication.

[Ebot]

I can’t access the actual article. I’d be interested to know the detail. The headline is quite alarmist but as ever the devil is in the detail!

[Paul1993et in reply to Ebot]

Hello Ebot, if you open de link you can click on: Looks like you clicked (?) Greetings Paul

[Ebot]

I did all that and read the abstract but couldn’t access the full article as password blocked.

[Paul1993et]

Try these: czemp.org/res/file/dokument...

[Ebot in reply to Paul1993et]

👍🏻 Thanks!

[Chemo01]

I’ve been on Hydroxy for 22 years , long term effect of Hydroxy 14 skin cancers on head and face and hands over the last 2 years even though I’ve always been very careful in the sun, also foot ulcers making it very difficult to walk far, specialists are pretty sure this is down to very very long use of Hydroxy so just beware of it’s long time use