Are immature cells bad and why do I need another bone marrow biopsy?

[billybrock]

Have been MF for 15 months and being treated with Ruxolitinib. Not showing any symptoms and feel well, other than an enlarged spleen.

Blood counts are good, except for a slightly lower Haemaglobin concentrate, and slightly increased white cells.

My last blood test showed some immature velds, so they ha be booked me in for another bmb.

This sounds serious anyone else been in this situation?

[Mazcd Partner MPNVoice]

Hi Billybrock, glad to hear that you are feeling well. It might be worth speaking to your specialist nurse about this, for some advice and reassurance, it might be that they want to have another BMB result on file to measure the changes, this is often the case. Best wishes, Maz

[billybrock in reply to Mazcd]

Hi Maz , I have a phone consultation on 21st September with one of Prof Harrison’s team, and will ask. They should have a. Blood test report detailing the immature cell situation

Billybrock

[clubdino]

Blast cells can be found in the blood when myelofibrosis is progressing. So it depends if they found blast cells or just slightly immature cells. Blast cells are the most immature cell and are more serious. Slightly immature cells would be a normal finding in myelofibrosis. I'm glad you are feeling well.

[billybrock in reply to clubdino]

Hi Clubdino, many thanks for your reply. I’ll have to wait till the results of the biopsy to see which they are.

Out of curiosity, your name suggests you May be a Dean Martin tribute act. Am I close?

[clubdino in reply to billybrock]

Haha no...my dog's name is Dino. 😄

[billybrock in reply to clubdino]

I did notice you were female after asking the question.ha ha!