My husband is 32, and has just been diagnosed with ET (negative for JAK2, CALR, MPL and BCR ABL) and we are waiting on further info. His platelet count is very very high and not budging yet - around 1.7m despite taking high doses of Hydroxycarbomide for a week now (about 4g a day). All other blood cells are normal and only stage 1 fibrosis in marrow.
The haematologist said today that his blast cells were irregular shapes and sizes which has me terrified it’s leukemia. She’s not mentioned this and is taking it to a multidisciplinary meeting to discuss further then we’ll
Know more .
This is all very very new and we’re struggling to get our head round all this new info as it is.
Does anyone know how long the meds take to work to bring platelets down?
If he’s negative for BCR-ABL mutation, what could these abnormal size and shaped blast cells mean?
I know you aren’t doctors but I wondered if anyone had any experience of this. I’m really overwhelmed!