Exercise and Et

[Petsch]

Does exercise lower or raise platelets. And if it raises them how many days before blood work should I avoid working out

[Wyebird]

Hi, all I know is that exercise helps me.

[Hidden in reply to Wyebird]

I agree 100%

[PeterET]

Keeping fit & active is the best thing you can do to help yourself. Don't think it actually affects platelet count but cannot do any harm. There was a thread on here a few days ago concerning fatigue & exercise may be worth checking out.

[largodomingo1981]

Hi everyone! I have never read in the research literature that you have to stop exercising before a blood test. Here you have a very recent research article about the relation between MPNs, fatigue and exercise: "Associations between Fatigue, Physical Activity, and QoL in Patients with Myeloproliferative Neoplasms" (2018): onlinelibrary.wiley.com/doi...

- Abstract and conclusion of the article:

Background: Patients with Philadelphia‐chromosome negative Myeloproliferative Neoplasms (MPNs) report fatigue as the most common symptom and contributing significantly to reduction in their Quality of Life (QoL). Targeted non‐pharmacological intervention to increase levels of physical activity is suggested as a fatigue‐reducing and QoL‐enhancing intervention in MPN patients. The interrelationship between physical activity, fatigue, and QoL have, to our knowledge, never been reported.

Methods: We analyzed data from 1,807 MPN patients. The primary analysis included a multiple regression model allowing fatigue to mediate the relationship between physical activity and QoL.

Results: We herein report the first and the largest study of patients with MPNs, in whom we have investigated the interrelationship between fatigue, physical activity, and QoL. Sedentary patients were more likely to report fatigue compared to highly active patients. There was a negative association between fatigue and QoL and there was a positive association between physical activity and QoL. There was no interaction between fatigue and physical activity in the association with QoL.

Conclusion: We found positive associations between level of physical activity and QoL, independently of fatigue being present. More research is needed before physical activity can be introduced as a targeted intervention to reduce fatigue and increase QoL in the management of patients.

[ChelseaF]

I was just recently reading about this. From what I have found “exhaustive” exercise (whatever that means) can cause a rise in platelet counts nearly immediately. They are released from the spleen and lungs. If my memory is right the increase averaged somewhere in the neighborhood of 80,000. I would imagine this increase would last the life span of platelets which is about 7-10 days. I will try to find what I read to link here. I would guess that with regular exercise this levels out, but I haven’t seen any data for that.

[ChelseaF]

I did a little more research and for the life of me I cannot find the article I mentioned previously. I did find some others. Most report more modest and transitory changes in platelet count. Here is one that references several studies:

kheljournal.com/archives/20...

I wouldn’t worry much about the effects on your counts before testing from what I’m reading here.

[Petsch in reply to ChelseaF]

Thank you for your help. After reading what you sent I’m still not sure. Every study seems to say something else but I think I will not exercise day before blood work.