I would like to know if anyone had any migraine and neck stiffness issues? I thought I was doing so well only a few weeks into Peg but the other week I had 5 migraines, 4 in one week and 3 in a row, which is more than I had before diagnosed with PV... my counts are brilliant. I had some iron which took well, my platelets literally 420 from being over 700 for years, but yet if this is a side effect then it is ruining me, I literally can't do anything and although I am self employed just been signed off work etc... don't want to be doom and gloom want to be positive it's unrelated and it will pass, sadly I got another migraine at 5am yesterday and I get aura and the hangover is awful, I can just about type this but I can't read it. blurred vision is so bad..... I always get an aura.. I also noticed last night a mouth ulcer - I have tried not to look at all the side effects as then I believe sometimes you start having them all... I was on 45mg Peg every 2 weeks but now decided with team that I would go every 3 weeks.