Hi, I am writing this on behalf of my husband who has MF. Both medications have stopped working now to a degree, Hydrea and Rux. My husband is to start radiation treatment next week to try and shrink his spleen which is massive. His platelets a couple of days ago were only 65. His specialist wants him to have blood administered in two days time, which will be the first transfusion for him. I am wondering if this is now the beginning of regular infusions. I don't contribute much to this site, but I read everything that comes through and it seems that once the blood trans start it is then just a continuous thing that happens. I wonder if anyone on this regime can let me know.