I’m at the end of my tether! I’m 51 & have had headaches & migraines since my teens. I’ve tried painkillers, triptans, amitriptyline, propranolol and I’ve been on Topamax for a year (100mg a day) and the daily headaches are back with a vengeance. I’m desperate. The pain is really bad and is ruining my life and I feel I have run out of options. What next?