Curved Penis - Early sign of Peyronie's Disease ?

[zorinner]

New to this forum. I'm in my late-30s and my penis seems to be getting increasingly curved as years past (see pic). It is also similarly curved when erect. It doesn’t affects negatively sexual intercourse (at least not yet) and I feel no pain.

It is not so much the aesthetics of it as it is more about the fact it seems to worsen with time that worries me. I'm getting more and more self-conscious about it. Is this a cause for concern? Is this an early sign of Peyronie diseases? Is there a medication I can take to stop the process? I feel I might be over-reacting here, but seeking advice. Thanks

[MrMac99]

Hi Man,

I have a curve as well I think I always had it a bit and it is possibly getting a little worse overtime as well. how long have you had it? Do your head twist a bit as well?

[draco54]

Cant really tell if its Peyronie's Disease only an urologist can.But as far as ive read on the internet for solutions theres surgical which is really risky, xiaflex i think its the first fda approved drug for peyronies but i think its expensive,ive read some people that some kind of exercise help, and recently ive seen that some people say that shockwave therapy may help. When i tried to mesure my curve it was 25-30 degrees off.

[Galen70]

Peyronies disease is caused by the build up of plaques at the base of the shaft of the penis. You can usually feel them . Some penile curavature is normal , but if its new and progressive you should get an assessment by a urologist.

[zorinner]

Thanks guys... and no the head is fine, it's not twisted ... just the shaft has shown on the picture. I can't say exactly when it started but I know my penis was straight when I was in my 20s. I've heard about xiaflex, but I haven't really investigated further. From what I'm gathering here and there, if there is no pain, then I shouldn't worry too much. In any event, I'll try to see an urologist just to be sure.

[DrNewman]

Peyronie's disease (PD) is an accumulation of collagen in the penis that creates a scar, producing a deformity and pain in the erectile state, that affects between 1%-8% of men. ANDROMEDICAL laboratory proposes a new strategy to treat PD based on combined therapy of platelet-rich fibrin matrix (PRFM or activated-PRP) with Andropeyronie, a penile traction device (PTD) designed to treat penile curvatures. Now urologists, their patients and health insurance companies may have a cost-effective alternative to collagenase and surgery for effectively treating Peyronie's disease, without side effects of other therapies.

In 2013 the US-FDA approved the use of collagenase (CCH) for its treatment. Collagenase is an enzyme that breaks the peptide bonds of collagen, but medical studies showed that effectiveness was limited to a 33% correction of penile curvature. In 2013, Dr. Martínez-Salamanca (Spain) carried out a hospital study with the penile traction device called Andropeyronie to treat Peyronie's disease in the acute phase, achieving a 60% correction of the curvature. In 2015 the American Urological Association recommends treating Peyronie's disease with combined collagenase therapy and Peyronie's plaque remodeling, done with manual exercises or with a soft progressive force for a few hours a day with a penile traction device (PTD). Medical protocol.

In 2018 Dr. Terlecki (USA) published a clinical study on the use of autologous platelet-rich plasma (PRP) in Peyronie's disease whose conclusions were that the activated-PRP or PRFM appears to be a safe and feasible treatment, more than 80% of patients improved in their degree of curvature. Evidence suggests that platelets play an important role in tissue repair, vascular remodeling and inflammatory and immune responses through secretion of growth factors, cytokines and chemokines. Thus, injection of PRFM could combine mechanical disruption of the plaque, via needle fracture, while simultaneously neutralizing destructive inflammatory processes in an effort to promote a better wound-healing response and stabilize the disrupted plaque. It is important to note that collagenase injection does not address appropriate wound healing or regeneration of the damaged tissue.

In 2013 Dr. Chung (Australia) demonstrated that penile traction translates mechanical stimuli into a chemical response leading to activation of cell proliferation. In 2019 Dr. Romero (Spain) published a clinical study demonstrating that the use of a penile traction device reduces the need of cycles of collagenase in patients with Peyronie's disease.

The world of urology is advancing rapidly and clinics are beginning to use this promising combined therapy of platelet rich plasma with penile traction therapy in hopes of wound healing and tissue regeneration. New treatment options for Peyronie's disease are opening up, with benefits for patients, urologists and health insurance companies. Therapy of PRP with PTD is an effective treatment without side effects, easily performed in the doctor's office and a cost-effective alternative to other therapies.

[Danniel78]

Hi I was diagnosed from Peyronies disease few months ago and I am using Andropeyronie. I'm very happy so far and my penis looks mor estrigh now... I was a bit scared because I wanted to avoid a surgery due to its side effects. Finally I found a medical study which convinced me to start using Andro device:

The penile traction device used in this study was Andropeyronie.

jsm.jsexmed.org/article/S17...

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Regards,