I am yet to have a definitive diagnosis as I seem to be able to test negative to all auto immune tests. I have a long history of urticaria, and stiffness in my joints on waking or after sitting,which I ignored for a long time. I had pleurisy of unknown cause, (I don't smoke or have asthma and I am in my early 30's) and always felt overwhelmingly tired. I thought I was just weak and that I needed to get on with life. Then six months ago I woke up with swollen hands/fingers and so sore I couldn't move them. From there on in I have had swollen knee joints foot pain/swelling etc i have a good Rheumy who has put me on pred, hydroxychloroquine and methotrexate the only thing that keeps me under control though is pred. I came off almost two weeks ago and I have had a massive flare and been very unwell. I know he will want me to go back on the pred but taking these drugs worry me, I understand that they help me function but are the side effects worse? Also does anyone else have terrible palpitations/tightness in the chest? I still feel unsure of the diagnosis though my Rheumy isn't. Apologies for all the questions I feel very unwell and could do with hearing if anyone has been through similar any advice would be welcome. Thank you.