Liver issues

[Margas]

Hi! I have been taking hidroxicloroquine and prednisolone for 3 years but my gama GT levels are too high. From 40 in June 2019 , 104 in December 2019 and 250 at the moment. I don't drink alcohol anymore and gave up Topiramate so that my liver has less medication to process. Has anyone gone through a similar situation? Can it be liver fatigue because of my lupus medication? Thanks.

[Kat136]

Hi Margas, I was on pred and placquenil and methotrexate but so far my liver has been ok. I am due to have more bloods done next week. I have had to stop placquenil because of retinal toxicity, am now on 6 monthly rituximab. I did have liver problems with leflunomide, so that turned out to be a no go. I would have a good discussion with your GP And Rheum about what it means and what is best done about it, if anything at this stage. It is always a balancing act, benefit vs risk. Make sure you get your say in any discussion. Good luck.

[Margas in reply to Kat136]

Thank you, Kat. The abdominal scan will give some answers, too. Unfortunately I'll have to wait until the 29th. Due to the pandemic, we having delays in our Portuguese health system.

[MrsDarbyshire]

Hi, I was told liver function has to be good before being allowed hydroxachloraquin as a treatment, infact, I had to have liver function tests first. I would be asking prescribing doctor if it is still safe to be on the medication, better to be safe, and ask those important questions.

Take care.

[Margas in reply to MrsDarbyshire]

Thank you for answering. My liver has been ok until last December. Yesterday I had a vídeo appointment with my internist and he asked an abdominal scan. It can be the gallbladder, he said.

[MrsDarbyshire in reply to Margas]

I hope they get to the bottom of this for you. Xx