Confused: Hi, I'm new here and could really do with... - LUPUS UK

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Confused

EllieE profile image
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Hi, I'm new here and could really do with some help please. Since 2012 I have tested positive for dsdna antibodies levels have been between 51 - 67 through out the years. I saw a rheumatologist between 2012 -2015 with symptoms such as achey body, tiredness, headaches and brain fog. I was told a possible connective tissue disorder could be developing but as my ana was negative there was not enough medical evidence to make a diagnosis. I was discharged from rheumatology in 2015 but have still had symptoms on and off. In September 2018 I went to my gp as I felt so awful again and she ran some tests. My ana cam back positive this time 1:160 and she referred me back to rhuematology. This week I received a phone call from the rheumatologist who advised I have tested positive for lupus as the ds dna test is positive again, but all other tests including ana is negative. During this phone call i was offered some medication but said I would rather wait and discuss at my next appointment in a couple of months. So I know that something is not right because I feel so awful but is there enough evidence here for me to be taking a medication such as Hydroxychloroquine? Has anyone been diagnosed with lupus on dna antibodies and symptoms alone? Would the positive ana test I had in September have any relevance? I am worried that I may end up taking a medication for something I do not have.

Any advise would be greatly appreciated.

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EllieE
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Bebe76 profile image
Bebe76

Hi EllieE,

Anti-dsDNA antibodies are very specific for lupus, while ANA is not. Also, ANA levels can fluctuate, or even be seen in some healthy people. Diagnosis is made based on a variety of criteria. These websites might help:

lupusuk.org.uk/getting-diag...

lupusuk.org.uk/diagnosis/

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