Anti dsdna

[cathylou]

Can you test positive and then negative on anti dsdna dna?

[Jill41]

Well I'd have thought so once u on meds a while they should alter ya bloods to make u feel better so your positive should go to negative ,

[Buffy14 in reply to Jill41]

I have had positive dsdna for 16 years even when I'm well and the disease is well controlled my bloods still all positive , the antidsdna figure fluctuates and is higher during a flare .

[Penguintaz]

Hi Cath

There have been quite a few posts about this, basically the result for this test isn't actually "positive" or "negative".

They do ratio testing so like how much antidsa do you have per this much blood (or something). Like seeing how many parts sugar are in water. And if you go past a certain ratio it's considered "positive" as in the antidsa is high enough.

It can change depending on medications, how well you are. time it's taken, lots of variables!

So it should not be the only factor taken into account when they are diagnosing you.

Hope this helps!

[Chanpreet_Walia LUPUS UK]

Hi Cath30088,

Yes, it is possible to experience a change in results. Lower disease activity due to control from medication and other factors can cause this to happen in some lupus patients. To learn about dsdna antibodies and why they are specific in people with lupus, click here: lupusuk.org.uk/getting-diag...