Hi everyone! I would be grateful if anyone could tell me about their experiences with aza. I have SLE and am on hydroxychloroquine and 15mg of pred. I have been started on Azathioprine for 4 days now. I'm really hoping it will work so I can reduce my prednisolone. The trouble is, within minutes of taking the Azathioprine I get a cracking headache that makes me feel pretty terrible. The first day I took it I felt very nauseated but this seems to have mostly passed. My question is, has anyone else suffered from these headaches and did they go once the drug has had a chance to settle into your system? All help greatly appreciated, thank you!