Abiraterone acetate with/out LHRH therapy.
New German paper below [ 1 ], announcing a clinical trial. " The trial will assess radiographic progression-free survival after 12 months of ...
Transdermal Estradiol update
A few months ago I had asked if anyone had experience with transdermal estradiol ( tE2 ) and Richard Wassersug, PhD responded to my post with...
News from ESMO 2017.
Johann de Bono from Royal Marsden gives a summary of the PCa sessions at the European Society for Medical Oncology [ ESMO ] meeting [ 1 ]. de...
free Testosterone [fT] & survival.
This follows on from my response to the YONSA post. From a recent paper [ 1 ]:...
The Importance Of Regular Scans
Hi everyone. I am posting this here tonight because I feel that it is so important that all of you brave men ask for scans to be carried out ...
Belated Introduction and Bio
Hello All: I'm 67, Dx in 2-17 with stage 4 PCa, 1 bone met. In 6-16, PSA was at 10, Ratio of free T to total was 0.12, so my urologist recomm...
Morgentaler & Testosterone Flare
New paper below. Abraham Morgentaler's Saturation Model states that PCa cells have all the testosterone [ T ] they can use at T levels in the...
HOT FLASHES – Why? What to do?
We often hear prostate cancer patients recommending to other prostate cancer patients regarding hot flashes: get “ MEGACE! ” – NOT for prosta...
Alternate hormone treatment
We keep talking about Lupron or Zoladex, etc. , for hormone depletion....
Melatonin is a hormone produced by the pineal gland at night. Production is tied to the circadian cycle, but can be cut short upon exposure t...
Transdermal Estrogen and Bone Mineral Density
Transdermal estrogen patches are sometimes used as an alternative to the traditional Luteinising Hormone-Releasing Hormone Agonists ( i.e. Lu...
Low PSA with a Gleason 8 diagnosis
I was diagnosed with prostatitis and BPH ( Benign Prostate Hyperplasia ) in 2001, but since my PSA level remained around 1.5 for the next sev...
Bicalutamide (Casodex) plus Dutasteride (Avodart)
New Dutch study 1 ] below. The rationale behind the combination of Casodex & Avodart was articulated in a 2009 paper [ 2 ]:...
Synatchen test results
Here is Sophia's synatchen test results perhaps someone could explain them too me ? Free T4 17 Cortisol profile varying between 110 and 181 b...
QOL paper from the PATCH trial
New study. Our own Richard Wassersug is one of the authors....
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Any New Suggestions for Dealing With Increasingly Debilitating Cognitive, Affective and Physical SEs from ADT?
Dx advanced PCa in 12, 2016 at age 66. Gleason 4+4=8, PSA high was 20, one suspected met at hip....
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