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COVID survivors may be at a greater risk of developing Parkinson’s–like symptoms, researchers warn. What to know to protect your health
[u]
However grim the findings, the team’s study resulted in some positive news: ALS drug riluzole, diabetes drug metformin, and cancer drug
appear to prevent the aforementioned type of neurons from becoming infected with COVID and, thus, losing their ability to function properly[/u]."
[u]
However grim the findings, the team’s study resulted in some positive news: ALS drug riluzole, diabetes drug metformin, and cancer drug
appear to prevent the aforementioned type of neurons from becoming infected with COVID and, thus, losing their ability to function properly[/u]."
Bolt_Upright
in
Cure Parkinson's
8 months ago
EGFR p.L747_T751de
Hi, Dad’s oncologist has stopped the Erlotinib as last scan in Jan showed tumour growth. Private Liquid biopsy result just back, mutation EGFR p.L747_T751de. No treatment offered by NHS, oncologist thinks will be more harmful to dad but how does he know for sure? I read some PubMed data that restarting
Hi, Dad’s oncologist has stopped the Erlotinib as last scan in Jan showed tumour growth. Private Liquid biopsy result just back, mutation EGFR p.L747_T751de. No treatment offered by NHS, oncologist thinks will be more harmful to dad but how does he know for sure? I read some PubMed data that restarting
Adaughter
in
The Roy Castle Lung Cancer Foundation
6 months ago
Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved?
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Hidden
in
Advanced Prostate Cancer
2 years ago
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Help and advice please.
Hello again everyone. I have just started on Tagisso which my doctor said is unlikely to work because my tumour doesn't have the right genetic 'make up'. But I live in hope, what else is there. He also said that if it didn't work there was nothing left. Over the past 2 years I have had Afatinib, immunotherapy
Hello again everyone. I have just started on Tagisso which my doctor said is unlikely to work because my tumour doesn't have the right genetic 'make up'. But I live in hope, what else is there. He also said that if it didn't work there was nothing left. Over the past 2 years I have had Afatinib, immunotherapy
sally70
in
The Roy Castle Lung Cancer Foundation
2 years ago
Radiotherapy
Hi just an update Have stage 4 lung but seems to be stable last scan showed my hip has been nibbled so having to have 5 rounds of radiotherapy Got my last bit of welding tomorrow I don’t Know if anybody else has had diarrhoea but Iv been terrible even a biscuit ! Anyway I’m still taking afatinib and
Hi just an update Have stage 4 lung but seems to be stable last scan showed my hip has been nibbled so having to have 5 rounds of radiotherapy Got my last bit of welding tomorrow I don’t Know if anybody else has had diarrhoea but Iv been terrible even a biscuit ! Anyway I’m still taking afatinib and
Rusty821
in
The Roy Castle Lung Cancer Foundation
3 years ago
A large injection of hope required. Please.
I was diagnosed with stage 4 lung cancer in early 2020 and was given the targeted therapy Afatinib. This was initially most effective but gradually stopped working and so the cancer spread further in the lungs. I then had five consecutive radiotherapy sessions which reduced the size of the main tumour
I was diagnosed with stage 4 lung cancer in early 2020 and was given the targeted therapy Afatinib. This was initially most effective but gradually stopped working and so the cancer spread further in the lungs. I then had five consecutive radiotherapy sessions which reduced the size of the main tumour
sally70
in
Lung Cancer Support
3 years ago
Need to stay strong - some hope ? (too early though)
In February, 2021, Inhibikase initiated clinical batch manufacturing and final product formulation of IkT-001Pro, the Company's prodrug formulation of
Imatinib
, designed as a potentially safer, better tolerated treatment for
Imatinib
-sensitive cancers such as stable-phase Chronic Myeloid Leukemia (CML
In February, 2021, Inhibikase initiated clinical batch manufacturing and final product formulation of IkT-001Pro, the Company's prodrug formulation of
Imatinib
, designed as a potentially safer, better tolerated treatment for
Imatinib
-sensitive cancers such as stable-phase Chronic Myeloid Leukemia (CML
John_morris71
in
Cure Parkinson's
3 years ago
Rash
Hi Iv been on 50mg afatinib now for 14 months though I struggle with the rash Iv got antibiotics if it gets too bad just wondering if if ever settles on it’s own
Hi Iv been on 50mg afatinib now for 14 months though I struggle with the rash Iv got antibiotics if it gets too bad just wondering if if ever settles on it’s own
Rusty821
in
The Roy Castle Lung Cancer Foundation
3 years ago
Makeup
Hi there Can anybody recommend a makeup that is suitable for rash prone skin I am on afatinib 50mg and have a red face at the moment 🙈though I won’t wear anything while I have it but after it’s gone I would like to get some slap on.
Hi there Can anybody recommend a makeup that is suitable for rash prone skin I am on afatinib 50mg and have a red face at the moment 🙈though I won’t wear anything while I have it but after it’s gone I would like to get some slap on.
Rusty821
in
The Roy Castle Lung Cancer Foundation
4 years ago
Face rash
Hi I’m on afatinib 50mg have been ok but Iv got a rash on my face nose is blocked and eyebrows all dried up I look like Iv be burned any ideas how to relieve would be appreciated
Hi I’m on afatinib 50mg have been ok but Iv got a rash on my face nose is blocked and eyebrows all dried up I look like Iv be burned any ideas how to relieve would be appreciated
Rusty821
in
The Roy Castle Lung Cancer Foundation
4 years ago
After 10 mnths on Afatinib my tumour regrew.My consultant described it as behaving atypically. Does this mean it has changed to small cell.
NSCLung cancer changing to small cell.
NSCLung cancer changing to small cell.
sally70
in
Lung Cancer Support
4 years ago
Is anyone on Imatinib for Systemic Mastocytosis and has the KITD816V mutation?
Link below says that it is to be used "for disease without the KIT[D816V] mutation". https://www.nice.org.uk/guidance/gid-ta10503/documents/final-scope https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=98850
Link below says that it is to be used "for disease without the KIT[D816V] mutation". https://www.nice.org.uk/guidance/gid-ta10503/documents/final-scope https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=98850
MastoMan
in
The UK Mastocytosis Support Group
4 years ago
Started taking Exjade for iron overload from transfusions
Other patients took the gamble to try rux and
imatinib
and lost their gamble so I feel I owe my opportunity to them. Pure research.
Other patients took the gamble to try rux and
imatinib
and lost their gamble so I feel I owe my opportunity to them. Pure research.
skodaguy
in
MPN Voice
4 years ago
has anyone been on exjade
I have benefited from the development of both
imatinib
and ruxolitinib so fell I have a duty to pay back to those patients willing and brave enough to go through trials to develop those drugs.
I have benefited from the development of both
imatinib
and ruxolitinib so fell I have a duty to pay back to those patients willing and brave enough to go through trials to develop those drugs.
skodaguy
in
MPN Voice
4 years ago
Skin rash
Hi I was diagnosed with stage 4 lung cancer in February and I am now taking afatinib and the tumour has shrunk thank goodness tho now after all this time my arms and stomach have broke out in the “rash” I was told to plaster myself in cetriban but was wondering does anybody have any tips
Hi I was diagnosed with stage 4 lung cancer in February and I am now taking afatinib and the tumour has shrunk thank goodness tho now after all this time my arms and stomach have broke out in the “rash” I was told to plaster myself in cetriban but was wondering does anybody have any tips
Rusty821
in
The Roy Castle Lung Cancer Foundation
4 years ago
Trying to keep busy
I personally have problems getting motivated. I am watching too much rubbish on the tele, eating too many crisps and ice cream. I am about to run out of goodies. Hopefully my next Sainsburys delivery will have some of the treats I ask for. :) I am very lucky that I have a tiny patio and some pots so
I personally have problems getting motivated. I am watching too much rubbish on the tele, eating too many crisps and ice cream. I am about to run out of goodies. Hopefully my next Sainsburys delivery will have some of the treats I ask for. :) I am very lucky that I have a tiny patio and some pots so
nikkidolls
in
The Roy Castle Lung Cancer Foundation
4 years ago
Adenocarcinoma of Lung
Hi ! I’m new to this . My husband was diagnosed with metastatic adenocarcinoma of lung cancer (T4N3M1A) last month. He is on Afatinib the last two weeks but he is suffering from all three blowup of the side affects in the first week , mouth sore/ ulcers , , diarrhoea, face n chest rashes. Has been in
Hi ! I’m new to this . My husband was diagnosed with metastatic adenocarcinoma of lung cancer (T4N3M1A) last month. He is on Afatinib the last two weeks but he is suffering from all three blowup of the side affects in the first week , mouth sore/ ulcers , , diarrhoea, face n chest rashes. Has been in
Ace467
in
The Roy Castle Lung Cancer Foundation
5 years ago
New member
Ive been on
imatinib
400mg since diagnosis and the main side effect being chronic fatigue. Just recently the fatigue has gotten worse and the consultant said its nothing to do the meds or illness.
Ive been on
imatinib
400mg since diagnosis and the main side effect being chronic fatigue. Just recently the fatigue has gotten worse and the consultant said its nothing to do the meds or illness.
Swimmer19
in
Leukaemia Support
5 years ago
A quick question before I forget it about ,,Acalabrutinib
Anyway, my quick question ,,, is Acalabrutinib a drug that you take for a long period of time ,,,, like
Imatinib
...... my understanding with
Imatinib
is most people take it until it stops working.,,, This is just a general question not about people one studies or other things.
Anyway, my quick question ,,, is Acalabrutinib a drug that you take for a long period of time ,,,, like
Imatinib
...... my understanding with
Imatinib
is most people take it until it stops working.,,, This is just a general question not about people one studies or other things.
michaelmac
in
CLL Support
5 years ago
Target Therapy for NSCLC stage 3 with EGFR mutation ?
My husband recently had results confirming the re-occurrence of his lung cancer. As a second line treatment he is being offered a target treatment. His oncologist is trying to get a new treatment funded for him called Dacomitinib. Is anyone using this new drug, and if so how is it going so far? We have
My husband recently had results confirming the re-occurrence of his lung cancer. As a second line treatment he is being offered a target treatment. His oncologist is trying to get a new treatment funded for him called Dacomitinib. Is anyone using this new drug, and if so how is it going so far? We have
e-priestman
in
The Roy Castle Lung Cancer Foundation
5 years ago
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