Experiences with

Imatinib

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Hi, Dad’s oncologist has stopped the Erlotinib as last scan in Jan showed tumour growth. Private Liquid biopsy result just back, mutation EGFR p.L747_T751de. No treatment offered by NHS, oncologist thinks will be more harmful to dad but how does he know for sure? I read some PubMed data that restarting

Doxazosin, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize

Hello again everyone. I have just started on Tagisso which my doctor said is unlikely to work because my tumour doesn't have the right genetic 'make up'. But I live in hope, what else is there. He also said that if it didn't work there was nothing left. Over the past 2 years I have had Afatinib, immunotherapy

Hi just an update Have stage 4 lung but seems to be stable last scan showed my hip has been nibbled so having to have 5 rounds of radiotherapy Got my last bit of welding tomorrow I don’t Know if anybody else has had diarrhoea but Iv been terrible even a biscuit ! Anyway I’m still taking afatinib and

I was diagnosed with stage 4 lung cancer in early 2020 and was given the targeted therapy Afatinib. This was initially most effective but gradually stopped working and so the cancer spread further in the lungs. I then had five consecutive radiotherapy sessions which reduced the size of the main tumour

In February, 2021, Inhibikase initiated clinical batch manufacturing and final product formulation of IkT-001Pro, the Company's prodrug formulation of Imatinib, designed as a potentially safer, better tolerated treatment for Imatinib-sensitive cancers such as stable-phase Chronic Myeloid Leukemia (CML

Hi Iv been on 50mg afatinib now for 14 months though I struggle with the rash Iv got antibiotics if it gets too bad just wondering if if ever settles on it’s own

Hi there Can anybody recommend a makeup that is suitable for rash prone skin I am on afatinib 50mg and have a red face at the moment 🙈though I won’t wear anything while I have it but after it’s gone I would like to get some slap on.

Hi I’m on afatinib 50mg have been ok but Iv got a rash on my face nose is blocked and eyebrows all dried up I look like Iv be burned any ideas how to relieve would be appreciated

NSCLung cancer changing to small cell.

Link below says that it is to be used "for disease without the KIT[D816V] mutation". https://www.nice.org.uk/guidance/gid-ta10503/documents/final-scope https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=98850

Other patients took the gamble to try rux and imatinib and lost their gamble so I feel I owe my opportunity to them. Pure research.

I have benefited from the development of both imatinib and ruxolitinib so fell I have a duty to pay back to those patients willing and brave enough to go through trials to develop those drugs.

Hi I was diagnosed with stage 4 lung cancer in February and I am now taking afatinib and the tumour has shrunk thank goodness tho now after all this time my arms and stomach have broke out in the “rash” I was told to plaster myself in cetriban but was wondering does anybody have any tips

I personally have problems getting motivated. I am watching too much rubbish on the tele, eating too many crisps and ice cream. I am about to run out of goodies. Hopefully my next Sainsburys delivery will have some of the treats I ask for. :) I am very lucky that I have a tiny patio and some pots so

Hi ! I’m new to this . My husband was diagnosed with metastatic adenocarcinoma of lung cancer (T4N3M1A) last month. He is on Afatinib the last two weeks but he is suffering from all three blowup of the side affects in the first week , mouth sore/ ulcers , , diarrhoea, face n chest rashes. Has been in

Ive been on imatinib 400mg since diagnosis and the main side effect being chronic fatigue. Just recently the fatigue has gotten worse and the consultant said its nothing to do the meds or illness.

Anyway, my quick question ,,, is Acalabrutinib a drug that you take for a long period of time ,,,, like Imatinib ...... my understanding with Imatinib is most people take it until it stops working.,,, This is just a general question not about people one studies or other things.

My husband recently had results confirming the re-occurrence of his lung cancer. As a second line treatment he is being offered a target treatment. His oncologist is trying to get a new treatment funded for him called Dacomitinib. Is anyone using this new drug, and if so how is it going so far? We have