I was diagnosed with APS a couple of months ago. I take Aspirin for it and see a Rheumatologist. I also have Osteoarthritis, Neuropathy, Hashimoto's Thyroiditis and Vitamin D Deficiency. I also have weakness in my muscles, sometimes I think they are all affected. I find myself restricted in any activities. Just picking up the yard after a rain makes my leg muscles hurt, mainly my thigh muscles, and then my legs feel really heavy and it takes all I can do to lift them as I try to walk. When riding a bike I feel the same way. I have to get off and push the bike for my thighs begin to hurt so bad that I can no longer push the pedal. For awhile after that my legs again feel heavy and it's hard to walk. Is this associated with APS? Any advice would be appreciated.