So there I was, casually looking for one specific genetic mutation when I found out that I have the SNP that tags HLA-DQ2.5 (one of the main coeliac genetic mutations), plus 34 others associated with coeliac.
Put simply: I have a truckload of coeliac genetic markers.
This then begs the question: as I have tested positive for the aforementioned HLA-DQ2.5 (which is carried by 20-30% of the population) AND 34 others associated with coeliac, and as adopting a gluten-free diet has sorted out what was thought to be IBS and my whole-body intense itching, and as I start to itch intensely again within hours of ingesting anything with even a tiny amount of wheat in it, and as I already have one autoimmune disease...
What are the chances that I do actually have coeliac disease? I've never tested positive in the blood tests but then pre-gf I didn't exactly hammer the gluten-containing foods anyway. My GP thinks this is interesting but is putting her money on a wheat allergy. I will be trying some pumpernickel this evening to test for a reaction to rye.
I know you're not doctors but I would like to know what you think.