I have been diagnosed for years with IBS, asthma, sinus problems, small intestinal gas, joint pain (unexplained), depression/anxiety, skin rashes (dermatitis/eczema). A few years ago I was told to quit using aspartame and margarine. I did so and substituted natural sugars like agave, molasses and honey instead. I have had allergy skin tests done that do not prove gluten intolerance and also IgA tests which prove gluten intolerance possibility. I have eliminated gluten from my diet and notice most of these symptoms go away except when I eat anything with gluten. I am from French, German, Austrian, Jewish and Native American ancestry. I also am a part of an American group of people called Melungeons who get diseases that appear to be Behcets and Mediterranean Familial Fever but have been most likely misdiagnosed because these people are poor coal miners. Those of us who have not used sugar, alcohol and eaten a great deal of bread/wheat are healthy while those who have get diabetes type II and cancer or heart disease. Those of us who have been through physical and emotional trauma seem to have it worse.