Preclinical: where are we with tumor ... - Fight Prostate Ca...

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Preclinical: where are we with tumor reversion?

Maxone73 profile image
3 Replies

Let's start 2025 with a post that makes us look at something that will be a revolution...it's good to start the new year with a dream.

Tumor reversion, the process of reprogramming cancer cells into normal-like cells, is emerging as a transformative approach to cancer therapy, offering a less toxic alternative to traditional treatments.

Recent breakthroughs include a 2024 study from KAIST, where researchers identified molecular switches to revert colon cancer cells through digital twin modeling, and findings from St. Jude’s Research Hospital, showing protein removal can reverse malignant cell identity in aggressive tumors like rhabdoid cancers.

Despite promising results, challenges remain, including decoding complex molecular pathways, modulating the tumor microenvironment, and scaling therapies for clinical use. Advanced tools like CRISPR, multi-omics, and AI are accelerating progress.

The potential is enormous, and AI can really help with its ability to find patterns and analyze huge amounts of data!

prostatewarriors.com/2025/0...

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Maxone73
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Broccoli24 profile image
Broccoli24

Positive news… another interesting route to keep an eye on… and other one that seems much less systemically damaging. Happy New year and THANKS for these posts.

Yzinger profile image
Yzinger

Great post Max. Has anyone here heard of a short mini series called "First in Human"?

It's really good imo. Sad too but good message I took from it. Must watch

Maxone73 profile image
Maxone73 in reply toYzinger

I will have to check it out!

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