New Target for Neuro Endocrine Prostate Cancer and does your circadian rhythm matter??

[NPfisherman]

Greetings,

A new mRNA target for NEPC was discovered in Australia (Oz) for NEPC development. The study revealed that a particular molecule, microRNA 'miR-194', can enhance this plasticity in prostate cancer, leading to the emergence of NEPC. Targeting that molecule led to inhibiting growth and development of NEPC.

sciencedaily.com/releases/2...

Can they use this target for development of an mRNA vaccine to prevent NEPC or slow it down dramatically?? The plot thickens in a good way...

For years, Scientists have been concerned on how your circadian rhythm effects your health. A study funded by the PCF shows that the clock gene CRY-1 is at higher levels in aggressive cancers and may play a role in blocking damage to cancer cells. from the article:

sciencedaily.com/releases/2...

The Science is Coming, so keep them peepers open !!!!

Don Pescado

[TFBUNDY]

Well Sir Nal. You're doing a pretty admirable job of extracting time, and expect to be looking for your posts in 30 years time. Maybe it's time to revisit the tumor microenvironment pH to keep the buggers down. Cheers...

[TFBUNDY]

107? You'll be in your prime

[TFBUNDY]

If you can find out the place where you will die.... NEVER GO THERE!

[NPfisherman in reply to TFBUNDY]

Be careful....you may be like the servant in the story, "Appointment in Samarra" and do yourself in...

Fish

[NPfisherman]

We have discussed this on your prior posts and it is why , like you, I believe that keeping cells senescent is so important. I take senolytics and try and do the healthy life style living things like diet, exercise, etc... The scientific development is happening so fast. With vaccines from my prior posts getting immune system responses that last, we may see a vaccine become a part of early treatment with an increase in PSADT and overall survival. Thanks for the reply...

Fish

[NPfisherman]

I take Optimized Resveratrol which has Quercetin, Fisetin, Trans-resveratrol and other goodies made by LE, and chamomile capsules, red wine daily, celery, parsley and oregano in my Italian Seasoning at Breakfast for Apigenin...I take green tea daily individually plus Kombucha...I feel that is enough, but looking for a Naturopath to do Lisanti protocol for CTC's on a 4 month basis...

Fish

[NPfisherman]

Trying to cover my bases to make vacation last... 3+ cups of coffee a day with 2 cups of green tea in the evening ... Enjoy the fishing... post picture of a big one...

Fish

[TheTopBanana in reply to NPfisherman]

What do both of you think about Ouabain?

[NPfisherman in reply to TheTopBanana]

For me, it is something I would not use as my heart rate runs low on metoprolol--50's-low 60's... I have a good EF and wouldn't mess with it....see below:

sciencedirect.com/topics/ne...

Just my 2 cents....

Fish

[TheTopBanana]

So happy to see a new post from you!

[NPfisherman in reply to TheTopBanana]

Well, the news came out and it had been almost 2 weeks so... gotta do what is essential....I do feel that others could provide information of interest, but people do what they do...

Fish

[GreenStreet in reply to NPfisherman]

Yes thanks a lot again Fish . Just catching up!

[NPfisherman in reply to GreenStreet]

You're welcome...as I say, the science is evolving so fast.... watching closely...

Fish