One of the problems with checkpoint inhibitors is that they do not work for everyone and target specific mutations only, but less than 50% of patients reap the benefits...
Wouldn't it be so much better if 50% or more gained benefit from these drugs being administered to them?? Scientists at Washington University School of Medicine believe they have found a way to achieve that purpose..
sciencedaily.com/releases/2...
One of the concepts that I have always held is that "combination therapies" would be the key to controlling prostate cancer and all cancers. The same concept that works so well in HIV.. As some of you know, I follow the vaccine trials with great interest...
Combining a checkpoint inhibitor with a vaccine to get a much greater response rate and involve Helper T's ..Will adding CpG or a CLEVER-1 inhibitor bring macrophages to the fight and do what people believe is impossible--a cure??
the abstract for the article--I may have to buy Nature:
nature.com/articles/s41586-...
The Science is Coming !!!
Don Pescado
New cancer treatment immuno therapy combined with guadecitabine in lung, breast, prostate bowel cancer makes cancer visible to immune sys