4BC Euploid?? : Hi everyone, We’ve... - Fertility Network UK

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4BC Euploid??

HelzBelzUK profile image
25 Replies

Hi everyone,

We’ve just had our 6th cycle. Out of 14 eggs collected, 11 were mature and 10 fertilised.

On day 3 we had 8 still going strong

Today (day 5) we have 2 blasts only grade 4BC.

I’m not sure how many others are showing potential but they’ll be left until tomorrow.

All embryos will be sent for pgta. Has anyone had a 4BC euploid? This was our last OE round before moving to donor and i’m numb with shock

Thank you xx

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HelzBelzUK profile image
HelzBelzUK
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25 Replies
Kitkat10 profile image
Kitkat10

hi, from my own experience, the grading didn’t seem to correlate with the genetic normality of the embryos. The embryologist told me that while the grading looks for certain characteristics, the genetic make up of the embryo is what determines their viability and that is not necessarily reflected by the grading which is based on appearance.

My own embryos were graded 5AB 5 AA but three of them were not viable and did not implant, whereas when I used DE, the grading was ‘less’ I think a 4BB , but worked first time and my little girl is perfect.

I didn’t really ever get enough embryos to PGT test so I’m sorry I can’t comment on that but I really think you have good chance of success and try not to worry too much about the grading. Good luck xx 🍀🍀

HelzBelzUK profile image
HelzBelzUK in reply toKitkat10

Thank you so much that’s really helpful xx

Yeahh I am aware that grading is irrelevant and its all about genetic make up xx Just seems unlikely that such a poor looking will be “normal”

Only the strong survive I suppose! xx

MiniCeeCee profile image
MiniCeeCee

I’m rooting for your little fighting embryos! I follow Dr Tim Child on insta, as he does some great live Q&A sessions. I recently asked him a question about whether embryos taking until day 6 (and embryos being a slightly lower quality), mean they are more likely to be abnormal or not. He did say there is a slightly higher chance of them being abnormal, the longer they take to get to blastocyst (ie, day 6 vs day 5) and the lower quality they are, but he didn’t reiterate it’s only a very small percentage difference. So to hold on hope, as there is still a great chance that that’s the one that works!

HelzBelzUK profile image
HelzBelzUK in reply toMiniCeeCee

Wow that’s really interesting x Thank you so much i’ll give him a follow xx

MiniCeeCee profile image
MiniCeeCee in reply toHelzBelzUK

Also meant to say he ‘did reiterate’, not ‘didn’t’ Sorry (typo!) x

LadyM2019 profile image
LadyM2019

ours is - 4BC low mosaic and 4CC euploid x

HelzBelzUK profile image
HelzBelzUK in reply toLadyM2019

ahh thank you so much that has made me feel so much better xxxx

LadyM2019 profile image
LadyM2019 in reply toHelzBelzUK

You’re very welcome, I know at least three other people at my clinic with euploid c grades. The grading doesn’t tell us so much now x

cass1063 profile image
cass1063

I had a 4DC (I know, I didn’t even think they bothered with Ds) come back euploid after the embryologist said it was likely none of mine would as they were such bad quality.

So a 4BC sounds pretty great to me 🖤 good luck!

HelzBelzUK profile image
HelzBelzUK in reply tocass1063

Wow that is amazing! Never heard of a D before! Thank you so much xxx

Vix12345 profile image
Vix12345

We recently did PGTA testing. We had 4 embryos to send off, a day 5 grade c, a day 6 grade a and 2 day 6 grade c. The day 5 grade c and day 6 grade a came back normal. The day 5 grade c had a score of 8.7 out of 10, and the day 6 grade a has a score of 5.1.

My clinic have said that once they are PGTA tested, the grading is sort of irrelevant as that's just a beauty contest really.

The other two embryos both had chromosome 22 issues and are unusable. I'm 39 (until next month) and egg collection was in October just past.

Hope this helps. Good luck x

HelzBelzUK profile image
HelzBelzUK in reply toVix12345

Thank you so much xxx

I’m hoping we may get one or two more today (day 6) to send away xx

We’re just so shocked at the drop off rate to lose 6 in one day! xx

Vix12345 profile image
Vix12345 in reply toHelzBelzUK

It's a lot. We had 12 eggs, 10 mature, 9 fertilised, all still ok day 3, and 1 on day 5, plus the 3 on day 6. It really is a steep drop off. Hopefully you get a couple of good ones to work with! Xx

HelzBelzUK profile image
HelzBelzUK in reply toVix12345

We’ve got 7 that are still cells and 1 that’s an early blast so i’m hoping that early blast has developed a bit more overnight xx

It’s frustrating because our clinic is in Greece and we don’t have any direct communication with the embryologist which annoys me. I’ll definitely be arranging some feedback xx Thank you xx

Vix12345 profile image
Vix12345 in reply toHelzBelzUK

Oh wow that does make it a little harder! But I have heard a lot of success stories with clinics abroad so 🤞🏻xx

Twiglet2 profile image
Twiglet2

we didn’t PGTA test but my little boy was a 4BC so it is very possible for the embryo to be healthy with that grade 🤗🤞🏽 xx

HelzBelzUK profile image
HelzBelzUK in reply toTwiglet2

Ahh that’s amazing congratulations xx The furthest we’ve ever got is a with a 4BC actually so I need to give the underdogs a bit more support! I was just shocked yesterday and immediately thought this is game over xx

Beclp profile image
Beclp

congrats on your 2 embryos

I got 4 from my last cycle

Transferred in order of how they looked

The first 3 didn’t take but the lowest graded one did and she’s a perfectly healthy little girl still growing inside 🩷

I don’t know the exact grading but I really didn’t hold much hope that it would work but what they look like doesn’t mean anything

Best of luck 🤞 🙌

HelzBelzUK profile image
HelzBelzUK in reply toBeclp

Ahh I love this! Huge congratulations

I think I was just in shock yesterday. I’ve done this enough times to know grading is subjective and also irrelevant.

I just really wanted a good amount to send for pgta to increase our chances. Fingers crossed our little under dogs make it xx

Beclp profile image
Beclp in reply toHelzBelzUK

never give up hope 💫💫

Sams25 profile image
Sams25

hey there, grading is really subjective and it was rubbish for me personally. My 5AA/AB transfers never worked.

However my frozen 3CC and 2BC embies, thawed really well, and I am now 38 weeks pregnant.. so I really hope that it works out for you guys too..

Best of luck and positive pants on!

HelzBelzUK profile image
HelzBelzUK in reply toSams25

Thank you so much xxx

The clinic contacted me earlier we’ve got another 2 day 6 4BC embryos so 4 in total xxx

25% chance of being euploid xx Everyone’s comments have given me so much hope and positivity today xxxx

Sams25 profile image
Sams25 in reply toHelzBelzUK

Good luck!!!! ❤️

Ford23 profile image
Ford23

Im currently sat here waiting to go in for csection to deliver our 4bc embryo. They are little fighters.All our top graded embryos failed to implant or ended in a chemical.

Best of luck with your transfer hun

Xxx

HelzBelzUK profile image
HelzBelzUK in reply toFord23

I love this xx Thank you so much and congratulations to you xx

We’re doing pgta so not doing a transfer just yet. Fingers crossed one of them is euploid xx

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