For those who often have Immature Eggs collected and discarded - thought this is worth a mention, not sure if it's commonplace/used in UK

[Lelo3479]

Edit - HFEA allowed an Oxford Clinic to complete this treatment in 2007, so not new technology, but my understanding is this was so patients who couldn't have stimulation such as those with PCOS could safely have egg collection. Other UK clinics also offer IVM as more natural procedure than being pumped full of drugs.

As regards the rescue IVM, I haven't found anything UK wise on a basic surface Google search.

Hiya, I've come across a procedure called IVM - In Vitro Maturation. Where they collect all eggs as normal and any that are immature are processed overnight in a procedure call Rescue In Vitro Maturation.

The procedure apparently matures most eggs and are comparably fertilised and euploid. However are less likely to produce blastocysts. I'm unsure of any other results. It was a study from the UAE.

I imagine it would be very handy for those with PCOS. But also, those who get very few eggs collected (so none are wasted) and those with lots of eggs and very few mature eggs.

I've only read a little about it (Remembryo - Embryoman), but I can't believe all clinics aren't completing the procedure as standard for everyone regardless.

If anyone has any personal knowledge would be worth a share on here x

[DianeArnold Partner Nurse Fertility Network UK]

Hi. As far as I know, this not available in the UK and not authorised by the HFEA. Diane

[Nakijo]

Thanks for sharing this. It's not available in my country, but its worth knowing what technology is helping us understand

[Lana89]

Hi lovely that’s very interesting never heard of that before just had a look and create offer it with a natural cycle thanks for sharing x

[minny_223]

Hello,

Thank you for raising as we don't hear enough about this process!

I was given rescue IVM during my most recent egg collection, at my clinic in the UK.

Of 5 eggs collected, 4 were immature. My clinic matured these 4 eggs in-lab for a further 24 hours. After which 2 eggs were suitably mature to go through to ICSI.

They both fertilized and one went on to form a 5BB blastocyst, suitable for freezing. I recently had it transferred, it implanted but sadly ended in a chemical pregnancy.

My understanding is that my clinic only offer rescue IVM in circumstances such as mine, where there are very low numbers of mature eggs collected. They don't advertise themselves as a clinic that do IVM.

When I asked my embryologist about the success rate of an embryo where the oocyte was matured in vitro, they said that they currently don't have enough data on it to make a call.

I hope this helps anyone reading. In my opinion it's definitely worth asking your clinic about it.

xx