down regulation with mild adeno ? Confused 😐

[Ladycoco20]

I need some advice as I’m so confused & feeling so lost

So far !!

3 transfers with down regulation- no success ( 5 embryos lost )

New clinic 1 transfers without it & new protocol following era results & finally the right amount of progesterone & we had a chemical 😞

our clinic are not concerned with my adenomyosis & want me to transfer again . After nearly 5 years of deivf my gut is telling me to speak up & stand up for myself with this one … we don’t want to waste our time money & mostly our precious embryos !

Any advice or experience welcome

Much love & thanks 🤍

[DianeArnold Partner Nurse Fertility Network UK]

Hi Ladycoco. Just hoping the ERA results will aid timing of transfer, so you need less down regulation. Good luck. Diane

[Twiglet2]

Hey lovely I hope you are doing okay! sounds like perhaps the conditions and timing were right and the embryo just wasn’t the right one on that last cycle? 🤞🏽I normally (after all the heartache) look at chemicals being a postive in that we were halfway there! hopefully the next one will work… If it’s fresh cycle you could test the embryos perhaps too? Xx

[Hopecontinues]

So sorry to hear about your chemical, I hope you are OK and being kind to yourself.

Regarding adenomyosis, if the clinic are not worried it probably means it is mild. That's what I have and only had a month down reg on a donor transfer.

It could just be that embryo, but if you really feel like you want a down reg, ask for it and push for answers. You are paying a lot of money for a service and are entitled to ask questions and have a say in your treatment. You want to know you have done everything you could.

Best of luck with your next transfer. I really hope it is the one. ☺️

[hazzahill12]

hi I have endo and adenomyosis. Had been trying for about 6/7 years before i got a diagnosis was told I was low ovarian reserve and early menopause. Had 3 rounds which were unsuccessful. My marriage then broke down and I had a year alone and when I met my current partner we started looking into it all together and I was finally sent for mri and diagnosed with adenomyosis. I had zoladex for about 6 months prior to my next IVF cycles and did long protocol and used buseriline to down reg straight after zoladex. after having transfers at day 5 which unfortunately were both unsuccessful. I did however then conceive naturally a couple of months after my last egg collection, the cycle I was going to try with a separate transfer ie a few months after eggs collection. To allow things to settle after stims.My son is now 16 months old. I then conceived again naturally when he was 6 months old and have an 8 week baby girl. Both pregnancy’s were a little tricky due to the adenomyosis drs believe, but it is possible and can happen. I was always told I had a 1% chance given the hostile womb environment from adenomyosis and my low AMH which was 3. I had paid for a multi cycle 3 rounds and was looking into surrogacy. Miracles can happen both of mine are proof. I truly hope you get your miracle. If you want to ask me anything or I can be of help please ask Xx