Results of ERA: Hello all, Some people... - Fertility Network UK

Fertility Network UK

56,132 members59,612 posts

Results of ERA

hifer profile image
31 Replies

Hello all,

Some people were keen to know my results from my ERA as they were either going through it themselves or thinking about it etc. So here goes:

1) The timing of the transfer is key and I need 6 full days of progesterone (not 5).

2) My lining isn’t happy- well I knew that to start with! The uterine natural killer cells are under activated making it difficult to implant (although I’ve had 2 natural pregnancies- lost both but we know for sure the second was due to abnormal embryo).

Treatment:

1) More progesterone obviously. One extra full day

2) An endometrial scratch to create inflammation of the lining (you all know how this works!)

3) Additional HcG administered (Ovitrelle) around transfer to help activate the lining.

All b***** confusing. Instead of feeling relieved we have results, I just feel so upset and emotional. Just seems we have so much against us.

Has anyone else had an under active lining?? I’m really not sure about having a scratch. The results/ research is patchy to say the least! I’m surprised it has been suggested. Any thoughts?

🙏 as always. Sorry for the essay!

Xx

Written by
hifer profile image
hifer
To view profiles and participate in discussions please or .
Read more about...
31 Replies
Cinderella5 profile image
Cinderella5

Hey, Ive been looking out for a post for you! I know this is a lot to take in however, look on the positive side.....you now know why your IVF cycles may not have been successful so far. The progesterone thing was a massive thing for us and we didn't get positives until we started to move the window up to nearer a 6 day window and getting it timed bang on seems to have helped us massively. The additional hCG shot is another way of naturally inducing your body to make more progesterone on top of what you'll be taking so this is also positive!! I know its tough to see through the shitty past but I think on reading this there is some light at the end of the tunnel here!!xxx

hifer profile image
hifer in reply toCinderella5

Ah thank you. I know I should be more positive and I feel like I’m coming round to that way of thinking. I wrote this post directly after we got off the phone with the consultant. I just felt so overwhelmed but I guess I’m getting used to all the news now. I know the progesterone has been absolutely key for you and your success 💕. I think I was a bit thrown by the fact that the scratch is now in my treatment plan! Research, as you well know, isn’t conclusive on this and I’m just starting to feel like a pin cushion! How are you doing lovely? Xx

Cinderella5 profile image
Cinderella5 in reply tohifer

I think its hard not to feel fed up.....its a bit like "what now??"!! Im glad that you are getting your head around things now and its such an important piece of the jigsaw especially when you are doing so much with PGS etc. No, Im not a fan of the scratch after reading the most recent evidence from the big UK study, not sure if you have seen it but link below. Do you know when you are going to try again? I heard that the ERA biopsy acts almost like a scratch so perhaps this covers it if you are going soon.

eshre.eu/ESHRE2020/Media/20...

Im doing ok thanks, still a bit nervy and not really sure if there is anything in there but hoping all is ticking along nicely.xx

hifer profile image
hifer in reply toCinderella5

Yes, thank you. I've also read that an ERA also acts like a scratch. None of the research I've read though correlates to my particular circumstances (and issues) so my husband's view is why not?! I'm struggling to find research into whether it works for under active uterine NK cells. In fairness, the consultant gave it a 50/50 chance of working with people in my circumstances (her research is based on UK wide). I can't get a cycle in before xmas anyway because of the clinic closing times so if I can get in a scratch and then do a cycle in Jan then I'm beginning to think why not! I'm not responding so well to drugs so I'm tempted to try something a bit more 'natural'. And I'm desperate!

Hoping you are feeling OK. Totally understand you being nervy. You've got this. Hopefully every week will get a little easier for you. xx

Cinderella5 profile image
Cinderella5 in reply tohifer

Well if you are ok about having it done then I guess that you know you have covered all bases whether you believe in it or not!

Yes, as the weeks go by it does get a little easier....its just my daft brain working over time that is the problem!! Ha ha ha xx

hifer profile image
hifer in reply toCinderella5

Oh god it’s not you being daft at all. I would be the same! Hopefully you’re getting some reassurance from the scans now but completely understand over thinking things- I’m the absolute queen of that! Have been thinking about you loads and sending you loads of positive vibes xx

Cinderella5 profile image
Cinderella5 in reply tohifer

It does help having scans but that reassurance doesn't last too long unfortunately! Maybe once I feel more "pregnant" then that will help.....probably not! Ha ha ha Awww thank you, Ive been thinking about you too. I am chuffed that you have something to work on which I obviously hoped would be the case. Onwards and upwards lovely!!xx

hifer profile image
hifer in reply toCinderella5

Thanks lovely lady 💕xx

Millbanks profile image
Millbanks

Hey lovely, that sounds pretty positive to me! You have some answers! I know it can be overwhelming having to make all of these changes, but far better to be able to do this than just blindly plough on, transfer after transfer. I suspect I will probably get similar results to you, especially with my lining not playing ball recently (although with didn’t opt for NKC)

Maybe once you’ve had time to process you’ll feel more positive about it xxx

hifer profile image
hifer in reply toMillbanks

I know, thank you. I’m starting to see the light now! I am starting to feel grateful that we do have results rather than nothing at all! Thanks for the positivity xx

Oooo have been hoping to hear an update from you! Can imagine that was complete information overload!! And I can quite see why you were so upset initially .. But hopefully now you have started to absorb it all? I think the key takeaway is there is new stuff to try that we have seen have a proven impact on other peoples success on here, so thats ultimately a good thing! I think it might have been even more upsetting if they had said 'everything is fine its just bad luck'?

Quick Q - the whole extra day of progesterone thing - does that mean they delay transfer or does that mean you start progesterone pre egg collection? I wasn't sure?

When will you get to try again? Sending you a huge hug, I really hope this is the start of good news for you xx

hifer profile image
hifer in reply to

Thanks lovely. Yes trying to absorb it all now and feels a bit more positive! Yes at least we have some answers and I should be grateful for that (and am getting there 😊).

I will be doing a FET so no more egg collections for me I don’t think. Pretty sure they will delay transfer by a day for me to give me 6 days of progesterone. I need a reasonably good amount of time to get my lining to thicken so don’t think they will reduce that time. I’m pre receptive so I need another day of progesterone. Just waiting for my protocol now.

Good question re starting again. Again just waiting to hear. Christmas puts a right spanner in the works! I will start another cycle this week so I’m hoping to get the scratch in before Xmas and then transfer after. Really not bothered about doing the scratch as research is so patchy about it but husband thinks we should give it a go!!

How’s things with you?

Xx

Hi hifer i agree with the rest. I think its very positive to have some answers and perhaps tweak any further treatment!

Did your clinic give you option? I mean that might be things that worked for other similar cases xx

hifer profile image
hifer in reply to

Thanks. No they didn’t really give me an option. They just told me what our plan was going forwards. Of course, it’s all optional so I could contest it if I wanted xx

Linda84Co profile image
Linda84Co

Thank you all these information, very informative, hope everything works out for you dear xx

hifer profile image
hifer in reply toLinda84Co

Thank you x

Lots8788 profile image
Lots8788

Sounds like some good things to tick off and increase chances for next round lovely. All the best for your next cycle 🤗😘 completely natural to feel like you do too but so glad they've found some things they can change and tweak to make this a success x big hugs x x

hifer profile image
hifer in reply toLots8788

Thanks lovely xx

ttcemmie profile image
ttcemmie

Hi hifer. I'm happy for you that you've got some answers and a plan going forward! That's some relief and joy even with the overwhelming information.

I understand what you mean about the scratch - I haven't seen that it's exactly "proven", but then it's also not going to harm.... Completely up-to-you and husband (with the guidance of the experts).

This post is making me feel really positive for your IVF treatment! So happy you've got some answers.

hifer profile image
hifer in reply tottcemmie

Ah thanks lovely. What a lovely positive message, thank you. Fingers crossed for our next moves.

How are you doing? Xx

ttcemmie profile image
ttcemmie in reply tohifer

I'm doing really well, thanks. xxx

hifer profile image
hifer in reply tottcemmie

I’m so so happy to hear that xx

Mara84 profile image
Mara84

Hi ! what a great post, thank you for sharing these information with us. best of luck with your next transfer xx

hifer profile image
hifer in reply toMara84

Ah thank you x

Catlady12345 profile image
Catlady12345

I think it’s great that you have some answers! Just use the knowledge to be positive about your next transfer 😊 I have my biopsy tomorrow for these tests and I’m so nervous 😩 x

hifer profile image
hifer in reply toCatlady12345

Ah thank you. Yes I’m feeling more positive today. Don’t be nervous! Are you nervous about the biopsy or the results? X

Catlady12345 profile image
Catlady12345 in reply tohifer

Both!! But yes very nervous about the biopsy itself.

Good luck with your next round wishing you lots of positivity xx

hifer profile image
hifer in reply toCatlady12345

Don’t be nervous of the biopsy. I was too and it was so much better than I expected. Just take a painkiller before as I’m sure your clinic have advised (I had to take buscopan) and you’ll be fine. It was all over pretty quick too. You’ll be fine.

Thanks for the positivity 😉xx

Millbanks profile image
Millbanks in reply tohifer

I had mine done last week and it really wasn’t as bad as I was expecting!! More just a very strange sensation than painful. You’ll be fine xx

hifer profile image
hifer in reply toMillbanks

Keen to hear your results too. 🤞 xx

Millbanks profile image
Millbanks in reply tohifer

I will let you know as soon as I hear!! Xx

Not what you're looking for?

You may also like...

era results

our era showed that we needed an extra day of progesterone. I just wondered how exact these results...
Boo718 profile image

ERA test results

Hello lovelies, I just had the results of my ERA test back and it shows that I am pre-receptive,...
Millbanks profile image

ERA results back advice please?

So my ERA, ALICE and EMMA results are finally back (after having to repeat it twice 🙄). Good news...
JadeH92 profile image

ERA test or just transfer final frosties?

Hi all, We've just had our review after the last transfer ended again in a BFN. While had the usual...
Purple276 profile image

Post Era Transfer

So after 3 failed FET (Own eggs/ 2 x blastocysts each transfer) i did an era test. I was pre...

Moderation team

See all
Claire_FNUK profile image
Claire_FNUKAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.