Hi I’m on fb a local fertility page someone was asking about genetics testing and where can it be done as our clinic doesn’t offer it. For people who’ve had it done can you suggest where uk only. We’re in Newcastle upon the area closest would be great.
Thanks
Not very close I’m afraid but we’ve just had PGS testing at IVI in London. X
Silly isn’t it our clinic is a genetics research centre but doesn’t do it
That’s surprising! Although the last clinic we were at didn’t offer it either. We didn’t move specifically for it but glad we did it.
Hi gcw. I would have thought that your clinic could recommend somewhere?? Good luck! Diane
Nope I have to say I’m disappointed with the clinic in general this isn’t for me but someone else who has been seen at the same clinic for a similar situation of reoccurring mc seems to be a gap in any advise or tests & treatment for people struggling with mc it’s just go away and keep trying as u can conceive on your own.
Hi gcw. Have you been referred to a recurrent miscarriage clinic if you have had 3 or more miscarriages? You should have. Diane
I had an appointment with the centre for life for fertility but I had just mc before the app so they used that app for reoccurring tests so I’ve had all the tests they offered no genetics. Then I’ve just been seen again for a review as it had been 10 mths I managed to get a amh and hsg even tho they weren’t really wanting to do them my amh is low at 3.4 but my hsg was clear. But now there’s nothing else. Said they’re not discussing ivf and we’d have to use donor eggs so best to keep trying on our own. I guess there’s only so much they can actually do.
Hi. Obviously it is up to both of you. Decide how much longer you are going to try on your own, then if no result, do give egg donation serious thought. It's OK for me to rabbit on, but in 23 years I've seen the heartbreak from low egg reserve turned into joy from using an egg donor. Remember too that you need a good few embryos to do genetic testing on. Thinking of you. Diane
I don’t think we’d go down the ivf route we’d have to self fund and my partner isn’t keen on donor, ivf or adoption. I have 2 older kids although I do want a baby with him I don’t feel sadness or longing of never being a mother more just frustrated I can’t. If he wanted too do ivf I’d do it for sure sooner rather than later I don’t have an issue with donor eggs but I think I would change clinic or at least have a chat to see what others had to offer.
Hey, I'm not sure if you mean genetic testing on the pregnancies that you lost to see I'd they were chromosomally normal. Although I think this may need to be on fresh tissue. That's the usual route for recurrent miscarriage along with tests like blood clotting disorders. It may not help with where you live but have you spoken to Tommy's?xx
The women who was asking me had made an app with Tommy’s but she has just found out she’s pregnant again and won’t see her if she’s pregnant I think she losses early so there’s nothing much to test I think she might mean testing for them.
Ahhh I see! That may well be what the problem is. I would have thought that even with early pregnancy they could test the tissue. It's a shame that there has been no help offered to even check for clotting disorders etc. Has she asked her local clinic about aspirin for clotting issues or prednisolone just in case she has NK cell issues?xx
I think she’s had the same reoccurring mc tests as me which were the blood tests for clotting etc thyroid and ultrasound
I presume they were all fine I think she’s looking for more
Ahhh I see! Has she asked early pregnancy if she losses again (really hope she doesnt) if she keeps the tissue, will they send it away for karyotyping if she's having recurrent miscarriage. Usually clinics will do that after 3 losses. I know in Scotland not all centres can do this but they can refer to east of Scotland genetics or West of scotland genetics etc.xx
Hi gcw104
I had 4 mcs, self-referred myself to Recurrent Miscarriage Clinic after 2 (as I'm over 40). After my third miscarriage I requested karyotyping of the tissue (you need to preserve the tissue from the miscarriage if it happens at home and take to clinic ASAP / or request before medical/surgical management happens). Our karyotyping revealed a chromosomal issue, so this made us eligible for further testing of mine & my husband's blood, to assess whether there was a Robertsonian gene translocation carried by one of us, rather than just a random mutation. From what I understand the likelihood of this being the reason for a miscarriage is very rare. Neither me nor my husband were identified as a carrier.
I'm not sure, but I don't think the NHS would automatically test for the robertsonian translocation without definitive evidence that it was a chromosomal issue that caused the miscarriage. Happy to be proven wrong though, as it is horrendous to think anyone would need to undergo further miscarriages to gather the evidence.
I hope this is useful to your friend, happy for her to PM me if she would like
x
Darlington 'London Womens Clinic' do genetic testing but i think it's on embryos.
I met a nurse who had 12 miscarriages, 3 at longer than 12w. Finally She had intramuscular progesterone injections and suppositories until 36 weeks and kept her baby. Have you had your progesterone checked to see if this could be an issue?
I’ve only had progesterone tests for ovulation which were ok
One Genetic Tested Embryo
PGS / PGD - Is genetic testing necessary?
11 blastocysts sent for genetic testing
