Zoladex not working?

[Wilsoc1]

Hi all,

I had my firstZoladex injection late November due to Stage 4 endometriosis and other than the usual agonising pain in December I have been pain free. It was like night and day and I finally felt I had my life back.

I have now had 5 monthly injections and felt some of my usual pain out of the blue three weeks ago.

This morning my pain came back worse than I’d ever had, to the point I had paramedics attend my house.

Has anyone else experienced the Zoladex implant stop working? I’m not sure what the next step is but I can’t go on like this again. I will call my endo nurse in the morning but on mentioning my pain 3 weeks ago she didn’t seem concerned and I’m not sure I’ll have another option offered to me.

[Hk23]

am on zoladex for heavy bleeding and at first it did wonders for me. I took a break from it for 4 months and just had my first injection after the break but am bleeding way more than i did before. I worry that it may not work this time i dont know if it fails bse there is no other options for me. I cant have the operation any time soon bse there are no appointments!! Hope your symptoms clear again. Take some pain killers if you can

[nats0802]

Hi Wilsoc1! Sorry to hear you’re still in pain with Zoladex. I’ve been on it for almost 2 years now, and it’s been working well for the most part. Are you on any sort of add back therapy, HRT? I ended up in A&E with extreme pain and bleeding, and started Kliovance shortly after. Since then I’ve only had spotting and occasional pain, normally a few days either side of getting the injection. It’s given me back a quality of life I didn’t think I’d manage to have! Hopefully you get sorted soon!

[Rocket14]

Sorry to hear what you have been going through. I had to come off zoladex as it caused me water infections and a kidney stone that had to be removed in theatre. If it continues ask for scan instead you have stone, its a rare side affect.

Get well soon.