After being diagnosed with endometriosis earlier this year, my most recent treatment are the Zoladex injections, and I've had 3 of my planned 6 shots. Initially the only side effects I had were hot flushes, but after my third shot I developed severely low moods; there were periods of time where I couldn't stop crying for hours, and felt negative about things in my life that previously I'd never worried about before. I even started doubting my relationship of almost two years with my boyfriend - I've never had any doubts previously, and I found this particularly distressing as I'm currently in the process of moving in with him and beginning a new career.
My older sister also used to suffer from endometriosis and had Zoladex injections when she was my age, and she also quickly developed depressed mood like me; she assures me it's just the medicine interfering with my hormones and my negative thoughts aren't really my own, so I shouldn't worry about it. I can't have HRT due to medical issues within my family, and so I'm planning to tell my doctor at my next appointment that I want to stop taking the Zoladex injections because the depression is too much of a strain for me.
I was wondering if anyone could advise me on how long the medicine will take to leave my system - is it likely my depressed mood will end at the end of the month following my last shot, or will it take longer? I'm considering taking a month off all medication, so my hormones can regain some balance and hopefully my mood can improve before I try something new again.
Also, after Zoladex my sister went on the Depo Provera shot and this was highly effective at combating her endometriosis pain, and so I think this might be considered as my next step. Is depression a common side effect of Depo also? I feel quite nervous about going into anything which may cause low moods as bad as I've been having this past week and a half; I find the mental strain much more difficult than my physical symptoms!
Thanks for any advice anyone can give