All the GnRH drugs are known to cause depression in a significant number of patients on the drug. It is the No.1 side effect warning now put on the patient info leaflet.
freely available online on pdf medicines.org.uk/emc/medici...
I was GnRH (zoladex) only 3 years ago and depression wasn't even mentoned on some types of the drugs' advice leaflets- but following a campaign and insistance by the FDA in the US and others, the GnRH drugs must now carry a warning about depression - so in the past few months all the advice leaflets have been updated to include this warning. They should do the same about cognitive impairment - but don't mention it yet. The manufacturers of these drugs are reluctant to be open and honest and will only put the barest legal minimum requirement on the advice leaflets that they can get away with.
Please read the information leaflet - there is a lot of information on there nevertheless.
Depression is top of page 2, Joint pains is covered on page 4 - right column.
If depression is coming on - it can only get progressively worse if you stay on the drug - you may be offered anti-depressants but it is much safer to quit the Decapeptyl as that may also help with all the other side effects too.
If you have endo - you are put on the drug in the hope it improves your daily quality of life - and when the side effects become too much that your quality of life is not better but worse - then it is time to stop. You are not on it to cure or kill endo -the drugs don't do that - they simply render endo dormant for a short time.
Use the search box on the green bar at the top of the page and type in Decapeptyl
Other keywords are GnRH, Zoladex, Prostap, Lupron etc - there are THOUSANDS of previous discussions on the subject of these drugs and plenty more online generally if you use google
with websites dedicated to victims of the drugs who have found they are suffering long term side effects long after stopping the drugs.
lupronvictimshub.com collects all sorts of reports and research data on GnRH drugs including Decapeptyl.
Even if you stop the drug - you may still need anti-depressants to help you cope with depression resulting from the drug-but if you quit soon after getting the blues then you may not need any extra help and your body may recover the natural way. Best of Luck.