Inflammation in the Liver Reversed by Metformin

[namaha]

Metformin is the First line drug for Type 2 Diabetes. It is in use for the last more than 50 years and there is hardly any adverse side effects if taken in recommended dosage.

While a lot of research is still on to find out the exact mechanism of working , in the process science keeps finding out many other benefits other than blood glucose lowering properties.

During this ongoing Covid-19, it was found out that Metformin gives protection against covid19 infection for diabetes....

Now science find out that it helps reducing inflammation in the liver. Earlier it was found out that it helps in controlling NAFLD.

genengnews.com/news/inflamm...

[sandybrown]

Thank you.

The diabetes drug metformin—derived from a lilac plant that’s been used medicinally for more than a thousand years—has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes. Yet scientists don’t fully understand how the drug is so effective at controlling blood glucose.

Now, researchers at the Salk Institute say they have shown the importance of specific enzymes in the body for metformin’s function. In addition, the new work showed that the same proteins, regulated by metformin, controlled aspects of inflammation in mice, something the drug has not typically been prescribed for.

If the Scientists do not understand this medication controlling diabetes, how can the doctors understand? Are the doctors doing what they are told?