This article from Parkinson's News today focuses on the mitochondria and the possibility for minimally invasive blood tests for Parkinson's that could be developed.
Mitochondrial dysfunction partly explained by immune responses
"Study findings may lead to diagnostic testing based on blood samples"
parkinsonsnewstoday.com/new...
"The number of copies of mitochondrial DNA in the blood of people with Parkinson’s disease are not a biomarker of poorly functioning mitochondria — the source of energy that powers cells — but may instead reflect immune responses that occur outside the brain, a study found.
The findings, which run counter to previous thinking, may mean it’s possible to develop minimally invasive tests using blood samples to diagnose Parkinson’s disease. The study, “Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s disease,” was published in npj Parkinson’s Disease"