Vaxxinity - anti alpha synuclein vaccine ... - Cure Parkinson's

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Vaxxinity - anti alpha synuclein vaccine Phase 1 results are good.

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This is good research on a vaccine that is intended to reduce the clumping forms of alpha synuclein. This is an approach similar to Prasinezumab which is on track with promising results in later trials. Unlike Prasinezumab though this is presumably a one and done solution.

Too good to be true? Anyway, still a long way out.

medscape.com/viewarticle/ea...

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Discogs_discogs

insideprecisionmedicine.com...

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Discogs_discogs in reply toDiscogs_discogs

The link above is regarding VAXXINITY. The link below is to do with PRASINEZUMAB monoclonal antibody :

nature.com/articles/s41591-...

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kaypeeoh

it hasn't been proven that anti alpha synuclein is toxic?

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Ctime in reply tokaypeeoh

That is what I have always thought. Do we really know what alpha synuclein does and so how does "vaccinating" against it affect other systems. However, there is the evidence from PRASINEZUMAB that the approach works. In addition, my reading is that the Vaxxinity antibodies are designed to "preferentially bind to the oligomeric and fibrillar forms of alpha-synuclein." Presumably this means the "bad" or abnormal alpha synuclein.

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