Looking like Success with TTFD, HDT (High Dose Thiamine) 🤪

[Gcf51]

I feel absolutely marvelous...

Long story shortened: With my current stack*, I kept over-dosing on my B1 hcl oral, so I thought why not try TTFD again at a really small dose of TTFD, first I tried 1/2 tab of 5mg ALINAMIN F (TTFD) – I had an anxiety attack. So I cut to 1/4 (1/4 a tab of 5g of TTFD (1.25 TTFD is 8.3 mg of B1, less than the RDA, heck my B-complex has more than that).

I have only taken 1/4 for 2 weeks.

* Stack: Some of which are in and it’s continuations healthunlocked.com/cure-par....

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My brain storming: Wild crazy ideas followed up by yet another wild crazy idea (not in logical order and not all crazy).

- I always thought blood barriers only covered only the BBB.

- There is also the blood-nerve barrier (BNB) which isn’t as well studied because cells of the BNB haven’t been grown in the lab. pubmed.ncbi.nlm.nih.gov/216...

What if PD is a failure of the BNB and nerves are damaged, too? What if (HDT) is getting some Thiamine across the BNB to aid failing nerves?

-         Dap1948 's protocol is to start low, increase B1 slowly till the first signs of improvement, then stop increasing, and give it time to work.

- I wonder if my Trial of TTFD failed; because I did not start at a low enough dose, and my continual over dosing was because my doses were too high.

Some of my posts/comments have been; TTFD made me a B1 believer. I would like to see a study on TTDF for PD, what if they fortified foods with TTFD – could we wipe out PD.

Posts in a private conversation:

- I wrote a message to Fatty15, asking if B1 was capable with B1 therapy for PD. They replied, they have never of B1 Therapy for PD.

- I have ODed again on B1. I think I am back on track B1,

- I tried to cut back on C/L, but can’t.

- I am going to be very disappointed; if I can’t reduce my C/L and all that happens is I reduce my very cheap B1.

- I am not saying having to reduce B1 is a bad thing. I am thinking, B1 is life support for sick cells. With the Fatty15, I require less life support.

- ALINAMIN F is a prescription drug in Japan ALINAMIN F available in 5mg and 25mg. (In USA TTFD is a supplement). The company I ordered from wouldn’t accept my card charge, so I sent a wire transfer. They are currently out of stock mimaki-family-japan.com/ite...

[park_bear]

"BNB is a key structure controlling the internal milieu of the peripheral nerve parenchyma"

peripheral = outside the brain

[Gcf51 in reply to park_bear]

Thanks

[Gcf51 in reply to park_bear]

Diffusion barriers located in the intrinsic vessels of the PNS and the perineurium have the capacity to regulate the environment around the nerve fibers and to keep it away from the blood and the extracellular fluid outside the PNS. pubmed.ncbi.nlm.nih.gov/216...

[park_bear in reply to Gcf51]

All very well but why do you believe the peripheral nervous system should be a therapeutic target in Parkinson's?

[Gcf51 in reply to park_bear]

My belief is PD is a disease of the mind body connection. Slow response causes out of control feed back to the brain, resulting in tremor. My MDS did not disagree, saying possible.

[Gcf51 in reply to Gcf51]

Not exactly as explained to my MDS, it was more like: You tell your brain to hold your hand out steady, your mind senses your hand moved, so your brain moved your hand in the other direction, but too much, so repeat, setting up a vicious cycle, resulting in tremor.

[dadcor]

20mg Allithiamine once per week and also citicolin and uridine. 15 months already feel really good. Reduced C/L from 1000mg to 400-500mg mainly during the night to sleep well. Added also 1,5mg melatonin . Lots of exercises, mainly boxing, noncontact of course.. Started working and driving again. When the workload gets a bit more intensive take 100-200 C/L to cope. This is it. Hope this period would last for ever

[Gcf51 in reply to dadcor]

First success story I have heard of with TTFD. 20 mg week 2.85 per day. Only a little over twice my 1.25. 😁

Yesterday I accidentally missed a dose of C/L with no ill effects. I may be able to cut my C/L too. I have never taken any C/L at night. I have never had a problem with no C/L from 5pm to 5am.

I also take uridine.

[Gcf51 in reply to dadcor]

I can't go longer than 5 days without due to return of symptoms.... 🙃

My B1 Breaks seldom last more than a week.

[dadcor]

It is not a success story.. not yet No illusions! I am not cured, just found my sweet spot and now feel good. It was not easy, just the opposite.. Should persist really and be careful because it is very easy to overdose..

[Gcf51]

We may never be able to say cured. All we can hope to do is manage.