Latest Paper on Coordinated Reset from Tass

[Neurosmith]

Just published today, "Coordinated reset stimulation of plastic neural networks with spatially dependent synaptic connections."

Haven't read it yet, but it sounds like they've they're exploring customization/personalization of CR based on individuals' synaptic connections (if my deciphering of the science-speak is right). Looks like the results are based on their computational models.

Link to paper: frontiersin.org/articles/10...

[cgreg]

Hi Neurosmith. Thanks for posting about the paper. Have you found any updates re the status of the clinical trials?

[Neurosmith in reply to cgreg]

I checked the status of their trials a few days ago and saw no updates. Only one is currently happening.

[cgreg in reply to Neurosmith]

Which trial is currently ongoing? Is it the one using the first generation gloves by Synergic or is it a trial using the second generation gloves by Stanford?

[Boscoejean in reply to cgreg]

The first generation gloves by Synergic are in a clinical trial now at OHSU

clinicaltrials.gov/study/NC...

[cgreg in reply to Boscoejean]

Thanks.

[Neurosmith in reply to cgreg]

There's also a Stanford trial with the status of "Enrolling by Invitation"

classic.clinicaltrials.gov/...

[cgreg in reply to Neurosmith]

Thanks

[claudejgreengrass]

I might have been able to follow the math during my third year at Michigan Tech. Those days are far behind me.

[WinnieThePoo]

Another paper to boggle the mind but add little (nothing) to current glove projects. It is another paper of theory, and the concepts are significantly more relevant to DBS. This is because DBS uses precisely targetted electrical stimulation direct to the neuronal populations. vCR adds a mechanical transducer and a physiological network containing multiple mechanoreceptors of significantly different characteristics

So, by way of an example, regardless of the theoretical merits you couldn't use a pulse (as opposed to burst) stimulus, and consequently almost certainly couldn't use ab fCR of 21Hz

[Fed1000 in reply to WinnieThePoo]

Hi Winnie, how are you doing with your gloves?

[WinnieThePoo in reply to Fed1000]

Great Fed. They are an essential part of my management of my PD

[Fed1000 in reply to WinnieThePoo]

I am very happy for you. The real great man is you, Winnie.

[Boscoejean]

clinicaltrials.gov/search?c...